Anti-MCSF Antibody | Boster Immunoleader PB9562 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-MCSF Antibody

catalog :

PB9562

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

mouse, rat

application :

ELISA, immunohistochemistry - paraffin section

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-MCSF Antibody

Catalog Number :

PB9562

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Macrophage colony-stimulating factor 1(CSF1) detection. Tested with IHC-P, ELISA in Mouse;Rat.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: mouse, rat

Applications :

IHC-P,ELISA

Immunohistochemistry(Paraffin-embedded S ... :

Concentration: 0.5-1μg/ml; Tested Species: Mouse, Rat

ELISA :

Concentration: 0.1-0.5μg/ml; Tested Species: Mouse

Notes :

Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E. coli-derived mouse MCSF recombinant protein (Position: K33-E262). Mouse MCSF shares 80.9 % and 88.6% amino acid (aa) sequence identity with human and rat MCSF, respectively.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by SA1022 in IHC(P).

Background :

M-CSF (or CSF-1) is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival ofmonocytes, macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte/macrophage cell lineage. By interacting with its membrane receptor (CSF1R or M-CSF-R encoded by the c-fms proto-oncogene), M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.

Reference :

1. Fixe P, Praloran V (June 1997)."Macrophage colony-stimulating-factor (M-CSF or CSF-1) and its receptor: structure-function relationships". Eur. Cytokine Netw. 8 (2): 125–36. 2. Nemunaitis J (April 1993). "Macrophage function activating cytokines: potential clinical application". Crit. Rev. Oncol. Hematol. 14 (2): 153–71. 3. Stanley ER, Berg KL, Einstein DB, Lee PS, Pixley FJ, Wang Y, Yeung YG (January 1997). "Biology and action of colony--stimulating factor-1". Mol. Reprod. Dev. 46(1): 4–10.

Gene Name :

CSF1

Protein Name :

Macrophage colony-stimulating factor 1

Gene Full Name :

colony stimulating factor 1 (macrophage)

Synonyms :

Colony stimulating factor 1 (macrophage) antibody Colony stimulating factor 1 antibody Colony stimulating factor macrophage specific antibody CSF 1 antibody CSF-1 antibody CSF1 antibody CSF1_HUMAN antibody Csfm antibody Lanimostim antibody M CSF antibody M-CSF antibody Macrophage Colony Stimulating Factor 1 antibody Macrophage colony stimulating factor antibody MCSF antibody MGC31930 antibody Processed macrophage colony-stimulating factor 1 antibody

Uniprot ID :

P07141

more info or order :

Boster Immunoleader product webpage