Anti-DKK2 Antibody | Boster Immunoleader PB9551 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-DKK2 Antibody

catalog :

PB9551

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, rat

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-DKK2 Antibody

Catalog Number :

PB9551

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Dickkopf-related protein 2(DKK2) detection. Tested with WB in Human;Rat.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, rat

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat

Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived human DKK2 recombinant protein (Position: K34-I259). Human DKK2 shares 96% amino acid (aa) sequence identity with mouse DKK2.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Dickkopf-related protein 2 is a protein that in humans is encoded by the DKK2 gene. This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6).

Reference :

1. "Entrez Gene: DKK2 dickkopf homolog 2 (Xenopus laevis)". 2. Krupnik VE, Sharp JD, Jiang C, Robison K, Chickering TW, Amaravadi L, Brown DE, Guyot D, Mays G, Leiby K, Chang B, Duong T, Goodearl AD, Gearing DP, Sokol SY, McCarthy SA (Dec 1999). "Functional and structural diversity of the human Dickkopf gene family". Gene 238 (2): 301–13. 3. Wu W, Glinka A, Delius H, Niehrs C (2001). "Mutual antagonism between dickkopf1 and dickkopf2 regulates Wnt/beta-catenin signalling.". Curr. Biol. 10 (24): 1611–4.

Gene Name :

DKK2

Protein Name :

Dickkopf-related protein 2

Gene Full Name :

dickkopf WNT signaling pathway inhibitor 2

Synonyms :

Dickkopf 2 antibody Dickkopf gene 2 antibody Dickkopf homolog 2 antibody Dickkopf related protein 2 antibody Dickkopf WNT signaling pathway inhibitor 2 antibody Dickkopf-2 antibody Dickkopf-related protein 2 antibody Dickkopf2 antibody DKK 2 antibody Dkk-2 antibody Dkk2 antibody DKK2_HUMAN antibody hDkk 2 antibody hDkk-2 antibody hDkk2 antibody

Uniprot ID :

Q9UBU2

more info or order :

Boster Immunoleader product webpage