Boster Immunoleader

antibody

Anti-CTGF Antibody

PB9541

100 ug/vial

240 USD

polyclonal

rabbit

human, rat

western blot, immunohistochemistry - paraffin section

Anti-CTGF Antibody

PB9541

Polyclonal

Rabbit IgG polyclonal antibody for Connective tissue growth factor(CTGF) detection. Tested with WB, IHC-P in Human;Rat.

240 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human, rat

WB,IHC-P

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat

Concentration: 0.5-1μg/ml; Tested Species: Human

Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

E.coli-derived human CTGF recombinant protein (Position: R58-A349). Human CTGF shares 95.5% and 95.9% amino acid (aa) sequence identity with mouse and rat CTGF, respectively.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

CTGF, also known as CCN2 or connective tissue growth factor, is a matricellular protein of the CCN family of extracellular matrix-associated heparin-binding proteins (see also CCN intercellular signaling protein). CTGF has important roles in many biological processes, including cell adhesion, migration, proliferation, angiogenesis, skeletal development, and tissue wound repair, and is critically involved in fibrotic disease and several forms of cancers. The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. And the encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis.

1. Chen CC, Lau LF (April 2009). "Functions and mechanisms of action of CCN matricellular proteins". Int. J. Biochem. Cell Biol. 41 (4): 771–83. 2. Hall-Glenn F, Lyons KM (October 2011). "Roles for CCN2 in normal physiological processes". Cell. Mol. Life Sci. 68 (19): 3209–17. 3. Jun JI, Lau LF (December 2011). "Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets". Nat Rev Drug Discov 10 (12): 945–63.

CTGF

Connective tissue growth factor

connective tissue growth factor

CCN 2 antibody CCN family member 2 antibody CCN2 antibody Connective Tissue Growth Factor antibody CTGF antibody CTGF_HUMAN antibody Hcs 24 antibody Hcs24 antibody Hypertrophic chondrocyte specific protein 24 antibody Hypertrophic chondrocyte-specific gene product 24 antibody Hypertrophic chondrocyte-specific protein 24 antibody IBP-8 antibody IGF-binding protein 8 antibody IGFBP-8 antibody IGFBP8 antibody Insulin like Growth Factor Binding Protein 8 antibody Insulin-like Growth Factor-Binding Protein 8 antibody MGC102839 antibody NOV 2 antibody NOV2 antibody

P29279