Anti-HRPT2 Antibody | Boster Immunoleader PB9532 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-HRPT2 Antibody

catalog :

PB9532

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-HRPT2 Antibody

Catalog Number :

PB9532

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Parafibromin(CDC73) detection. Tested with WB in Human.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived human HRPT2 recombinant protein (Position: Q119-R520). Human HRPT2 shares 100% and 99.8% amino acid (aa) sequence identity with mouse and rat HRPT2, respectively.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Cell division cycle 73, also known as HRPT2, is a protein which in humans is encoded by the CDC73 gene. This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. And this protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.

Reference :

1. "Entrez Gene: CDC73 Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)". 2. Sood R, Bonner TI, Makalowska I, Stephan DA, Robbins CM, Connors TD, Morgenbesser SD, Su K, Faruque MU, Pinkett H, Graham C, Baxevanis AD, Klinger KW, Landes GM, Trent JM, Carpten JD (April 2001). "Cloning and characterization of 13 novel transcripts and the human RGS8 gene from the 1q25 region encompassing the hereditary prostate cancer (HPC1) locus". Genomics 73 (2): 211–22.

Gene Name :

CDC73

Protein Name :

Parafibromin

Gene Full Name :

cell division cycle 73

Synonyms :

C1orf28 antibody CDC 73 antibody Cdc73 antibody CDC73_HUMAN antibody Cell division cycle 73 antibody Cell division cycle 73 Paf1/RNA polymerase II complex component homolog antibody Cell division cycle protein 73 homolog antibody FLJ23316 antibody HPT JT antibody HPTJT antibody HRPT 2 antibody Hyperparathyroidism 2 (with jaw tumor) antibody Hyperparathyroidism 2 antibody Hyperparathyroidism 2 protein antibody HYX antibody Parafibromin antibody

Uniprot ID :

Q6P1J9

more info or order :

Boster Immunoleader product webpage