Anti-CACNA1F Antibody | Boster Immunoleader PB9530 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-CACNA1F Antibody

catalog :

PB9530

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-CACNA1F Antibody

Catalog Number :

PB9530

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Voltage-dependent L-type calcium channel subunit alpha-1F(CACNA1F) detection. Tested with WB in Human.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived human CACNA1F recombinant protein (Position: Q1843-L1977). Human CACNA1F shares 87.4% amino acid (aa) sequence identity with mouse CACNA1F.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Cav1.4, also known as the calcium channel, voltage-dependent, L type, alpha 1F subunit (CACNA1F), is a human gene. This gene encodes a multipass transmembrane protein that functions as an alpha-1 subunit of the voltage-dependent calcium channel, which mediates the influx of calcium ions into the cell. And the encoded protein forms a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Mutations in this gene can cause X-linked eye disorders, including congenital stationary night blindness type 2A, cone-rod dystropy, and Aland Island eye disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed.

Reference :

1. "Entrez Gene: CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit". 2. Boycott KM, Pearce WG, Bech-Hansen NT (2000). "Clinical variability among patients with incomplete X-linked congenital stationary night blindness and a founder mutation in CACNA1F.". Can. J. Ophthalmol. 35 (4): 204–13. 3. Wutz K, Sauer C, Zrenner E et al. (2003). "Thirty distinct CACNA1F mutations in 33 families with incomplete type of XLCSNB and Cacna1f expression profiling in mouse retina.". Eur. J. Hum. Genet. 10 (8): 449–56.

Gene Name :

CACNA1F

Protein Name :

Voltage-dependent L-type calcium channel subunit alpha-1F

Gene Full Name :

calcium channel, voltage-dependent, L type, alpha 1F subunit

Synonyms :

Aland island eye disease (Forsius Eriksson ocular albinism, ocular albinism type 2) antibody CAC1F_HUMAN antibody CACNA 1F antibody CACNAF antibody CACNAF1 antibody Calcium channel voltage dependent alpha 1F subunit antibody Calcium channel voltage dependent L type alpha 1F subunit antibody Cav1.4 antibody Cav1.4alpha1 antibody COD 3 antibody COD3 antibody CORDX 3 antibody CORDX antibody CORDX3 antibody CSNB2A antibody CSNBX 2 antibody CSNBX2 antibody JM 8 antibody JM8 antibody JMC 8 antibody JMC8 antibody Voltage dependent L type calcium channel subunit alpha F antibody Voltage gated calcium channel alpha 1F subunit antibody Voltage gated calcium channel subunit alpha Cav1.4 antibody

Uniprot ID :

O60840

more info or order :

Boster Immunoleader product webpage