Anti-cIAP2 Antibody | Boster Immunoleader PB9527 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-cIAP2 Antibody

catalog :

PB9527

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-cIAP2 Antibody

Catalog Number :

PB9527

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Baculoviral IAP repeat-containing protein 3(BIRC3) detection. Tested with WB in Human.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived human cIAP2 recombinant protein (Position: M1-K191). Human cIAP2 shares 69.8% amino acid (aa) sequence identity with mouse cIAP2.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Baculoviral IAP repeat-containing protein 3 (also known as cIAP2) is a protein that in humans is encoded by the BIRC3 gene. cIAP2 is a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified.

Reference :

1. "Entrez Gene: BIRC3 baculoviral IAP repeat-containing 3". 2. Liston P, Roy N, Tamai K, Lefebvre C, Baird S, Cherton-Horvat G, Farahani R, McLean M, Ikeda JE, MacKenzie A, Korneluk RG (February 1996). "Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes". Nature 379 (6563): 349–53. 3. Rothe M, Pan MG, Henzel WJ, Ayres TM, Goeddel DV (February 1996). "The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins". Cell 83 (7): 1243–52.

Gene Name :

BIRC3

Protein Name :

Baculoviral IAP repeat-containing protein 3

Gene Full Name :

baculoviral IAP repeat containing 3

Synonyms :

AIP 1 antibody AIP1 antibody API 2 antibody API2 antibody API2 antibody Apoptosis inhibitor 2 antibody Baculoviral IAP repeat containing 3 antibody Baculoviral IAP repeat containing protein 3 antibody Baculoviral IAP repeat-containing protein 3 antibody BIRC 3 antibody BIRC3 antibody BIRC3 antibody BIRC3_HUMAN antibody C IAP2 antibody C-IAP2 antibody CIAP 2 antibody CIAP 2 antibody CIAP2 antibody HAIP 1 antibody HAIP1 antibody HAIP1 antibody HIAP 1 antibody HIAP-1 antibody HIAP1 antibody IAP homolog C antibody IAP-1 antibody Inhibitor of apoptosis protein 1 antibody Inhibitor of apoptosis protein 1 antibody MALT 2 antibody MALT2 antibody Mammalian IAP homolog C antibody MIHC antibody MIHC antibody RING finger protein 49 antibody RNF49 antibody TNFR2 TRAF signaling complex protein 1 antibody TNFR2 TRAF signalling complex protein antibody TNFR2-TRAF-signaling complex protein 1 antibody

Uniprot ID :

Q13489

more info or order :

Boster Immunoleader product webpage