Anti-SOCS4 Antibody | Boster Immunoleader PB9506 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-SOCS4 Antibody

catalog :

PB9506

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-SOCS4 Antibody

Catalog Number :

PB9506

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Suppressor of cytokine signaling 4(SOCS4) detection. Tested with WB in Human.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived human SOCS4 recombinant protein (Position: M291-C440). Human SOCS4 shares 98% amino acid (aa) sequence identity with mouse SOCS4.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

SOCS4, also known as Suppressor of cytokine signaling 4, is mapped to 14q22.1. The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

Reference :

1. Bullock AN; Rodriguez MC; Debreczeni JE; Songyang Z; Knapp S. “Structure of the SOCS4-ElonginB/C complex reveals a distinct SOCS box interface and the molecular basis for SOCS-dependent EGFR degradation”. Structure, 2007 Nov. 2. Kobayashi D; Nomoto S; Kodera Y; Fujiwara M; Koike M; Nakayama G; Ohashi N; Nakao A. “Suppressor of cytokine signaling 4 detected as a novel gastric cancer suppressor gene using double combination array analysis”. World J Surg, 2012 Feb.

Gene Name :

SOCS4

Protein Name :

Suppressor of cytokine signaling 4

Gene Full Name :

suppressor of cytokine signaling 4

Synonyms :

CIS4 antibody Cish4 antibody Cytokine inducible SH2 protein 4 antibody DKFZp686J1568 antibody HSPC060 antibody SH2 domain containing SOCS box protein antibody SOCS-4 antibody SOCS-7 antibody SOCS4 antibody SOCS4_HUMAN antibody SOCS6 antibody SOCS7 antibody SSI4 antibody STAI4 antibody STAT induced STAT inhibitor 4 antibody STAT4 antibody STATI4 antibody Suppressor of cytokine signaling 4 antibody Suppressor of cytokine signaling 7 antibody

Uniprot ID :

Q8WXH5

more info or order :

Boster Immunoleader product webpage