Anti-SLC19A1 Antibody | Boster Immunoleader PB9504 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-SLC19A1 Antibody

catalog :

PB9504

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-SLC19A1 Antibody

Catalog Number :

PB9504

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Folate transporter 1(SLC19A1) detection. Tested with WB in Human.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence in the middle region of human SLC19A1 (202-231aa FLKRPKRSLFFNRDDRGRCETSASELERMN).

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Solute carrier family 19 (folate transporter), member 1, also known as SLC19A1 or RFC1, is a protein which in humans is encoded by the SLC19A1 gene. Transport of folate compounds into mammalian cells can occur via receptor-mediated or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. And RFC1 plays a role in maintaining intracellular concentrations of folate.

Reference :

1. "Entrez Gene: SLC19A1 solute carrier family 19 (folate transporter), member 1". 2. Lapenta V, Sossi V, Gosset P, Vayssettes C, Vitali T, Rabatel N, Tassone F, Blouin JL, Scott HS, Antonarakis SE, Créau N, Brahe C (April 1998). "Construction of a 2.5-Mb integrated physical and gene map of distal 21q22.3". Genomics 49 (1): 1–13. 3. Stanisławska-Sachadyn A, Mitchell LE, Woodside JV, Buckley PT, Kealey C, Young IS, Scott JM, Murray L, Boreham CA, McNulty H, Strain JJ, Whitehead AS (September 2009). "The reduced folate carrier (SLC19A1) c.80G>A polymorphism is associated with red cell folate concentrations among women". Ann. Hum. Genet. 73 (Pt 5): 484–491.

Gene Name :

SLC19A1

Protein Name :

Folate transporter 1

Gene Full Name :

solute carrier family 19 (folate transporter), member 1

Synonyms :

CHMD antibody FLOT 1 antibody FLOT1 antibody Folate transporter 1 antibody FOLT antibody IFC 1 antibody IFC-1 antibody IFC1 antibody Intestinal folate carrier 1 antibody Intestinal folate carrier antibody OTTHUMP00000115459 antibody OTTHUMP00000115460 antibody Placental folate transporter antibody Reduced folate carrier antibody Reduced folate carrier protein antibody REFC antibody RFC 1 antibody RFC antibody RFC1 antibody S19A1_HUMAN antibody SLC19A1 antibody Solute carrier family 19 member 1 antibody

Uniprot ID :

P41440

more info or order :

Boster Immunoleader product webpage