Anti-SGCA Antibody | Boster Immunoleader PB9503 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-SGCA Antibody

catalog :

PB9503

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-SGCA Antibody

Catalog Number :

PB9503

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Alpha-sarcoglycan(SGCA) detection. Tested with WB in Human;Mouse;Rat.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: mouse, rat Predicted to work with: human

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Mouse, Rat; Predicted Species: Human

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived human SGCA recombinant protein (Position: Q24-H387). Human SGCA shares 90.7% amino acid (aa) sequence identity with mouse SGCA.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Alpha-sarcoglycan is a protein that in humans is encoded by the SGCA gene. This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.

Reference :

1. "Entrez Gene: SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)". 2. McNally EM, Yoshida M, Mizuno Y, Ozawa E, Kunkel LM (Nov 1994). "Human adhalin is alternatively spliced and the gene is located on chromosome 17q21". Proc Natl Acad Sci U S A 91 (21): 9690–4.

Gene Name :

SGCA

Protein Name :

Alpha-sarcoglycan

Gene Full Name :

sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)

Synonyms :

50 DAG antibody 50 kDa dystrophin associated glycoprotein antibody 50 kDa dystrophin-associated glycoprotein antibody 50DAG antibody 50kD DAG antibody 59kDa antibody A2 antibody adhalin antibody ADL antibody Alpha SG antibody Alpha-sarcoglycan antibody Alpha-SG antibody Asg antibody DAG2 antibody DMDA2 antibody Dystroglycan 2 antibody Dystroglycan-2 antibody LGMD2D antibody sarcoglycan, alpha (dystrophin-associated glycoprotein) antibody SCARMD1 antibody Sgca antibody SGCA_HUMAN antibody

Uniprot ID :

Q16586

more info or order :

Boster Immunoleader product webpage