Anti-ATP1A1 Antibody | Boster Immunoleader PB9482 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-ATP1A1 Antibody

catalog :

PB9482

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, rat

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-ATP1A1 Antibody

Catalog Number :

PB9482

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Sodium/potassium-transporting ATPase subunit alpha-1(ATP1A1) detection. Tested with WB in Human;Rat.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, rat

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat

Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the N-terminus of human ATP1A1 (7-34aa RDKYEPAAVSEQGDKKGKKGKKDRDMDE), different from the related mouse sequence by three amino acids, and from the related rat sequence by four amino acids.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene.

Reference :

1. "Entrez Gene: ATP1A1 ATPase, Na+/K+transporting, alpha 1 polypeptide". 2. Dunbar LA, Caplan MJ (2001). "Ion pumps in polarized cells: sorting and regulation of the Na+, K+- and H+, K+-ATPases.". J. Biol. Chem. 276 (32): 29617–20. 3. Xie Z, Cai T (2004). "Na+-K+--ATPase-mediated signal transduction: from protein interaction to cellular function.". Mol. Interv. 3(3): 157–68.

Gene Name :

ATP1A1

Protein Name :

Sodium/potassium-transporting ATPase subunit alpha-1

Gene Full Name :

ATPase, Na+/K+ transporting, alpha 1 polypeptide

Synonyms :

A1A1 antibody AT1A1 antibody AT1A1_HUMAN antibody ATP1A1 antibody Atpa-1 antibody ATPase Na+/K+ transporting alpha 1 polypeptide antibody BC010319 antibody EC 3.6.3.9 antibody MGC3285 antibody MGC38419 antibody MGC51750 antibody Na K ATPase alpha A catalytic polypeptide antibody Na K ATPase catalytic subunit alpha A protein antibody Na(+)/K(+) ATPase 1 antibody Na(+)/K(+) ATPase alpha-1 subunit antibody Na+/K+ ATPase alpha 1 subunit antibody Na+/K+ ATPase 1 antibody Nkaa1b antibody Sodium potassium ATPase alpha 1 polypeptide antibody Sodium pump 1 antibody Sodium pump subunit alpha-1 antibody sodium-potassium ATPase catalytic subunit alpha-1 antibody Sodium/potassium transporting ATPase alpha 1 chain antibody Sodium/potassium-transporting ATPase subunit alpha-1 antibody

Uniprot ID :

P05023

more info or order :

Boster Immunoleader product webpage