Anti-AGTR1 Antibody | Boster Immunoleader PB9470 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-AGTR1 Antibody

catalog :

PB9470

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse

application :

western blot, immunohistochemistry - paraffin section

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-AGTR1 Antibody

Catalog Number :

PB9470

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Type-1 angiotensin II receptor(AGTR1) detection. Tested with WB, IHC-P in Human;Mouse.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, mouse

Applications :

WB,IHC-P

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Mouse

Immunohistochemistry(Paraffin-embedded S ... :

Concentration: 0.5-1μg/ml; Tested Species: Human

Notes :

Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the N-terminus of human AGTR1 (1-28aa MILNSSTEDGIKRIQDDCPKAGRHNYIF), different from the related mouse and rat sequences by one amino acid.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

Background :

AGTR1 is known as Angiotensin II Type 1 Receptor. Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. And it acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. Moreover, this gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene.

Reference :

1. "Entrez Gene: AGTR1 angiotensin II receptor, type 1". 2. Catt KJ, Mendelsohn FA, Millan MA, Aguilera G (1984). "The role of angiotensin II receptors in vascular regulation". J. Cardiovasc. Pharmacol. 6(Suppl 4): S575–86. 3. Higuchi S, Ohtsu H, Suzuki H, Shirai H, Frank GD, Eguchi S (2007). "Angiotensin II signal transduction through the AT1 receptor: novel insights into mechanisms and pathophysiology". Clin. Sci. 112 (8): 417–28.

Gene Name :

AGTR1

Protein Name :

Type-1 angiotensin II receptor

Gene Full Name :

angiotensin II receptor, type 1

Synonyms :

AG2S antibody Agtr 1 antibody Agtr1 antibody AGTR1_HUMAN antibody Agtr1a antibody AGTR1B antibody Ang II antibody Angiotensin II receptor type 1 antibody Angiotensin II type-1 receptor antibody Angiotensin receptor 1 antibody Angiotensin receptor 1B antibody AT 1B antibody AT 1r antibody AT1 antibody At1a antibody AT1AR antibody AT1B antibody AT1BR antibody AT1R antibody AT2R1 antibody AT2R1A antibody AT2R1B antibody HAT1R antibody Type 1 angiotensin II receptor antibody Type 1B angiotensin II receptor antibody Type-1 angiotensin II receptor antibody

Uniprot ID :

P30556

more info or order :

Boster Immunoleader product webpage