Anti-Vitronectin Antibody | Boster Immunoleader PB9458 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-Vitronectin Antibody

catalog :

PB9458

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry - paraffin section

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-Vitronectin Antibody

Catalog Number :

PB9458

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Vitronectin(VTN) detection. Tested with WB, IHC-P in Human;Mouse;Rat.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, mouse, rat

Applications :

WB,IHC-P

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Mouse, Rat

Immunohistochemistry(Paraffin-embedded S ... :

Concentration: 0.5-1μg/ml; Tested Species: Human

Notes :

WB: The detection limit for Vitronectin is approximately 0.25ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human Vitronectin (446-472 aa RVNLRTRRVDTVDPPYPRSIAQYWLGC), different from the related mouse sequence by two amino acids.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

Background :

Vitronectin, also known as VTN, is a protein that in humans is encoded by the VTN gene. The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. Also vitronectin serves to regulate proteolysis initiated by plasminogen activation. In addition, vitronectin is a component of platelets and is, thus, involved in hemostasis.

Reference :

1. "Entrez Gene: M Vitronectin". 2. Jenne D, Stanley KK (October 1987). "Nucleotide sequence and organization of the human S-protein gene: repeating peptide motifs in the "pexin" family and a model for their evolution". Biochemistry 26 (21): 6735–42. 3. Preissner KT, Seiffert D (January 1998)."Role of vitronectin and its receptors in haemostasis and vascular remodeling" ( SCHOLAR SEARCH). Thromb. Res. 89(1): 1–21.

Gene Name :

VTN

Protein Name :

Vitronectin

Gene Full Name :

vitronectin

Synonyms :

Complement S Protein antibody Epibolin antibody S Protein antibody S-protein antibody Serum Spreading Factor antibody Serum-spreading factor antibody Somatomedin B antibody Somatomedin-B antibody V75 antibody Vitronectin V10 subunit antibody Vitronectin V65 subunit antibody VN antibody VNT antibody VTN antibody VTNC_HUMAN antibody

Uniprot ID :

P04004

more info or order :

Boster Immunoleader product webpage