product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-SNAI3 Antibody
catalog :
PB9440
quantity :
100 ug/vial
price :
240 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human
application :
western blot
product information
Product Name :
Anti-SNAI3 Antibody
Catalog Number :
PB9440
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for Zinc finger protein SNAI3(SNAI3) detection. Tested with WB in Human.
Price :
240 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: human
Applications :
WB
Western blot :
Concentration: 0.1-0.5μg/ml; Tested Species: Human
Notes :
WB: The detection limit for SNAI3 is approximately 0.1ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Immunogen :
A synthetic peptide corresponding to a sequence in the middle region of human SNAI3 (155-178aa FHCHKPYHTLAGLARHRQLHCHLQ), different from the related mouse sequence by two amino acids.
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.
Background :
SNAI3 is a member of the SNAIL gene family, named for the Drosophila snail gene, which plays roles in mesodermal formation during embryogenesis. SNAI3 gene, was located between KIAA0233 gene and CBFA2T3 gene in human chromosome 16q24.3, a region affected in breast cancer, gastric cancer, hepatocellular carcinoma, ovarian cancer, and therapy-related myeloid leukemia with t(16;21)(q24;q22) translocation. Human SNAI3 gene was found to encode 292-amino-acid polypeptide with the N-terminal SNAG domain and five zinc finger domains. And Human SNAI3 mRNA was expressed in skin melanotic melanoma, lung epidermoid carcinoma, and germ cell tumor. Because SNAG zinc-finger proteins are transcriptional repressors implicated in carcinogenesis and embryogenesis, SNAI3 gene might be a potent target of pharmacogenomics in the field of oncology and regenerative medicine.
Reference :
1. Katoh M; Katoh M: Identification and characterization of human SNAIL3 (SNAI3) gene in silico. Int J Mol Med, 2003 Mar.
Gene Name :
SNAI3
Protein Name :
Zinc finger protein SNAI3
Gene Full Name :
snail family zinc finger 3
Synonyms :
MGC129606 antibody Protein snail homolog 3 antibody SMUC antibody SNAI3 antibody SNAI3_ HUMAN antibody Snail homolog 3 (Drosophila) antibody SNAIL3 antibody Zfp293 antibody Zinc finger protein 293 antibody Zinc finger protein SNAI3 antibody ZNF293 antibody
Uniprot ID :
Q3KNW1
company information
Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com
925.485.4527
headquarters: USA
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