product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-SLC2A2 Antibody
catalog :
PB9436
quantity :
100 ug/vial
price :
240 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human
application :
western blot, immunohistochemistry - paraffin section
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product information
Product Name :
Anti-SLC2A2 Antibody
Catalog Number :
PB9436
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for Solute carrier family 2, facilitated glucose transporter member 2(SLC2A2) detection. Tested with WB, IHC-P in Human.
Price :
240 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: human
Applications :
WB,IHC-P
Western blot :
Concentration: 0.1-0.5μg/ml; Tested Species: Human
Immunohistochemistry(Paraffin-embedded S ... :
Concentration: 0.5-1μg/ml; Tested Species: Human
Notes :
WB: The detection limit for SLC2A2 is approximately 0.1ng/lane under reducing conditions.
Tested Species: In-house tested species with positive results.
By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections.
Other applications have not been tested.
Optimal dilutions should be determined by end users.
Immunogen :
A synthetic peptide corresponding to a sequence at the C-terminus of human SLC2A2 (486-514aa ETKGKSFEEIAAEFQKKSGSAHRPKAAVE), different from the related mouse sequence by five amino acids, and from the related rat sequence by seven amino acids.
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).
Background :
SLC2A2, also known as Glucose transporter 2 (GLUT2), is a transmembrane carrier protein that enables protein facilitatedglucose movement across cell membranes. This gene encodes an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. The encoded protein mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. Mutations in this gene are associated with susceptibility to diseases, including Fanconi-Bickel syndrome and noninsulin-dependent diabetes mellitus (NIDDM). Alternative splicing results in multiple transcript variants of this gene.
Reference :
1. Froguel P, Zouali H, Sun F, Velho G, Fukumoto H, Passa P, Cohen D (July 1991)."CA repeat polymorphism in the glucose transporter GLUT 2 gene". Nucleic Acids Res. 19 (13): 3754.
2. Santer R, Groth S, Kinner M, Dombrowski A, Berry GT, Brodehl J, Leonard JV, Moses S, Norgren S, Skovby F, Schneppenheim R, Steinmann B, Schaub J (January 2002). "The mutation spectrum of the facilitative glucose transporter gene SLC2A2 (GLUT2) in patients with Fanconi-Bickel syndrome".Hum. Genet. 110 (1): 21–9.
3. Uldry M, Ibberson M, Hosokawa M, Thorens B (July 2002). "GLUT2 is a high affinity glucosamine transporter". FEBS Lett. 524(1-3): 199–203.
Gene Name :
SLC2A2
Protein Name :
Solute carrier family 2, facilitated glucose transporter member 2
Gene Full Name :
solute carrier family 2 (facilitated glucose transporter), member 2
Synonyms :
liver antibody Glucose Transporter 2 antibody Glucose Transporter GLUT2 antibody Glucose transporter type 2 antibody Glucose transporter type 2 liver antibody Glucose transporter, liver/islet antibody GLUT-2 antibody GLUT2 antibody GTR2_HUMAN antibody GTT2 antibody SLC2A2 antibody Solute carrier family 2 (facilitated glucose transporter) member 2 antibody Solute carrier family 2 facilitated glucose transporter member 2 antibody Solute carrier family 2, facilitated glucose transporter member 2 antibody
Uniprot ID :
P11168
more info or order :
company information

Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com925.485.4527
headquarters: USA
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