Boster Immunoleader

antibody

Anti-SSH3BP1 Antibody

PB9416

100 ug/vial

240 USD

polyclonal

rabbit

human, mouse, rat

western blot, immunohistochemistry - paraffin section

Anti-SSH3BP1 Antibody

PB9416

Polyclonal

Rabbit IgG polyclonal antibody for Abl interactor 1(ABI1) detection. Tested with WB, IHC-P in Human;Mouse;Rat.

240 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human, mouse, rat

WB,IHC-P

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Mouse, Rat

Concentration: 0.5-1μg/ml; Tested Species: Mouse, Rat; Predicted Species: Human

WB: The detection limit for SSH3BP1 is approximately 0.1ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence at the N-terminus of human SSH3BP1 (151-175aa HGVKWLKAKHGNNQPARTGTLSRTN), identical to the related mouse and rat sequences.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

SSH3BP1 is also known as ABI1. ABI1 is a human homolog of mouse Abl-interactor-1 (Abi1), mapped on 10p11.2. ABI1 participates in the transduction of signals from Ras to Rac by regulating Rac-specific guanine nucleotide exchange factor (GEF) activities. It dramatically promoted ABL1-mediated tyrosine phosphorylation of MENA, but not of other substrates. Abi-1 regulates c-Abl-mediated phosphorylation of Mena by interacting with both proteins. ABI1 plays a role in the leukemogenesis by translocating to MLL.

1. Tani, K.; Sato, S.; Sukezane, T.; Kojima, H.; Hirose, H.; Hanafusa, H.; Shishido, T. : Abl interactor 1 promotes tyrosine 296 phosphorylation of mammalian Enabled (Mena) by c-Abl kinase. J. Biol. Chem. 278: 21685-21692, 2003. 2. Taki, T.; Shibuya, N.; Taniwaki, M.; Hanada, R.; Morishita, K.; Bessho, F.; Yanagisawa, M.; Hayashi, Y. : ABI-1, a human homolog to mouse Abl-interactor 1, fuses the MLL gene in acute myeloid leukemia with t(10;11)(p11.2;q23). Blood 92: 1125-1130, 1998.

ABI1

Abl interactor 1

abl-interactor 1

Abelson interactor 1 antibody ABI 1 antibody Abi-1 antibody ABI1 antibody ABI1_HUMAN antibody Abl binding protein 4 antibody Abl interactor 1 antibody Abl interactor protein 1 antibody Abl interactor protein 1 long antibody Abl-binding protein 4 antibody AblBP4 antibody Ablphilin 1 antibody E3B1 antibody Eps8 binding protein antibody Eps8 SH3 domain binding protein antibody Eps8 SH3 domain-binding protein antibody Eps8-binding protein antibody Hssh3bp1 antibody Interactor protein AblBP4 antibody NAP1 antibody Nap1 binding protein antibody Nap1-binding protein antibody NAP1BP antibody Spectrin SH3 domain binding protein 1 antibody Spectrin SH3 domain-binding protein 1 antibody SSH3BP antibody

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