Anti-RANK Antibody | Boster Immunoleader PB9413 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-RANK Antibody

catalog :

PB9413

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse

application :

western blot, ELISA

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-RANK Antibody

Catalog Number :

PB9413

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 11A(TNFRSF11A) detection. Tested with WB, ELISA in Mouse.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: mouse

Applications :

WB,ELISA

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Mouse

ELISA :

Concentration: 0.1-0.5μg/ml; Tested Species: Mouse

Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E. coli-derived mouse RANK recombinant protein (Position: C35-S214). Mouse RANK shares 95.6% amino acid (aa) sequence identity with rat RANK.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Receptor Activator of Nuclear Factor κ B (RANK), also known as TRANCE Receptor, is a type I membrane protein that is expressed on the surface of osteoclasts and is involved in their activation upon ligand binding. RANK is also expressed on dendritic cells and facilitates immune signaling.RANKL (Receptor Activator for Nuclear Factor κ B Ligand) is found on the surface of stromal cells, osteoblasts, and T cells. By analysis of somatic cell and radiation hybrid panels, Anderson et al. (1997) mapped the RANK gene to 18q22.1.

Reference :

1. Suda T, Takahashi N, Udagawa N, Jimi E, Gillespie MT, Martin TJ (1999). "Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families". Endocr. Rev. 20 (3): 345–57. 2. Theill LE, Boyle WJ, Penninger JM (2002). "RANK-L and RANK: T cells, bone loss, and mammalian evolution". Annu. Rev. Immunol. 20: 795–823. 3. Wong BR, Josien R, Choi Y (1999). "TRANCE is a TNF family member that regulates dendritic cell and osteoclast function". J. Leukoc. Biol. 65 (6): 715–24.

Gene Name :

TNFRSF11A

Protein Name :

Tumor necrosis factor receptor superfamily member 11A

Gene Full Name :

tumor necrosis factor receptor superfamily, member 11a, NFKB activator

Synonyms :

Activator of NFKB antibody CD 265 antibody CD265 antibody CD265 antigen antibody EOF antibody FEO antibody LOH18CR1 antibody Loss of heterozygosity 18 chromosomal region 1 antibody mRANK antibody NFKB activator antibody ODFR antibody OFE antibody OPTB7 antibody Osteoclast differentiation factor receptor antibody OSTS antibody PDB 2 antibody PDB2 antibody RANK antibody Receptor activator of NF KB antibody Receptor activator of NF-KB antibody receptor activator of nuclear factor kappa B antibody TNFRSF 11A antibody TNFRSF11A antibody TNFSF11 antibody TNR11_HUMAN antibody TRANCE R antibody TRANCER antibody Tumor necrosis factor receptor superfamily member 11a NFKB activator antibody Tumor necrosis factor receptor superfamily member 11a activator of NFKB antibody Tumor Necrosis Factor Receptor Superfamily Member 11a antibody

Uniprot ID :

O35305

more info or order :

Boster Immunoleader product webpage