Anti-SNAIL Antibody | Boster Immunoleader PB9399 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-SNAIL Antibody

catalog :

PB9399

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-SNAIL Antibody

Catalog Number :

PB9399

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Zinc finger protein SNAI1(SNAI1) detection. Tested with WB in Human;Mouse;Rat.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, mouse, rat

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Mouse, Rat

Notes :

WB: The detection limit for SNAIL is approximately 0.1ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence in the middle region of human SNAIL(127-155aa AAFPGLGQVPKQLAQLSEAKDLQARKAFN), different from the related mouse sequence by six amino acids.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

The Drosophila embryonic protein SNAI1, commonly known as Snail, is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. And it is located in 16q24.3. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. It is studied that SNAIL gene may show a role in recurrence of breast cancer by downregulating E-cadherin and inducing anepithelial to mesenchymal transition.

Reference :

1. "Entrez Gene: SNAI1 snail homolog 1 (Drosophila)". 2. Davidson NE, Sukumar S (September 2005). "Of Snail, mice, and women". Cancer Cell 8(3): 173–4.

Gene Name :

SNAI1

Protein Name :

Zinc finger protein SNAI1

Gene Full Name :

snail family zinc finger 1

Synonyms :

dJ710H13.1 antibody Protein sna antibody Protein snail homolog 1 antibody Protein snail homolog antibody SLUGH2 antibody SNA antibody Sna protein antibody SNAH antibody SNAI antibody SNAI1 antibody SNAI1_HUMAN antibody Snail 1 homolog antibody Snail 1 zinc finger protein antibody SNAIL antibody Snail homolog 1 (Drosophila) antibody SNAIL, Drosophila, homolog of, 1 antibody SNAIL1 antibody Zinc finger protein SNAI1 antibody

Uniprot ID :

O95863

more info or order :

Boster Immunoleader product webpage