Anti-PTGER2 Antibody | Boster Immunoleader PB9386 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-PTGER2 Antibody

catalog :

PB9386

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-PTGER2 Antibody

Catalog Number :

PB9386

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Prostaglandin E2 receptor EP2 subtype(PTGER2) detection. Tested with WB in Human.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Notes :

WB: The detection limit for PTGER2 is approximately 0.1ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human PTGER2 (281-308aa TIFAYMNETSSRKEKWDLQALRFLSINS), different from the related mouse sequence by four amino acids, and from the related rat sequence by three amino acids.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Prostaglandin E2 receptor (53kDa), also known as EP2, is aprostaglandin receptor for prostaglandin E2. It is encoded by the human gene PTGER2. It may be associated with aspirin-induced asthma. PTGER2 is mapped to chromosome 14q22. This gene encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma.

Reference :

1. Smock, S. L., Pan, L. C., Castleberry, T. A., Lu, B., Mather, R. J., Owen, T. A. Cloning, structural characterization, and chromosomal localization of the gene encoding the human prostaglandin E2 receptor EP2 subtype. Gene 237: 393-402, 1999. 2. Sugimoto Y, Nakato T, Kita A et al. (2004). "A cluster of aromatic amino acids in the i2 loop plays a key role for Gs coupling in prostaglandin EP2 and EP3 receptors". J. Biol. Chem. 279 (12): 11016–26.

Gene Name :

PTGER2

Protein Name :

Prostaglandin E2 receptor EP2 subtype

Gene Full Name :

prostaglandin E receptor 2 (subtype EP2), 53kDa

Synonyms :

EP 2 antibody EP2 antibody Human prostaglandin E2 receptor antibody PE2R2_HUMAN antibody PGE receptor EP2 subtype antibody PGE2 receptor EP2 subtype antibody Prostaglandin E receptor 2 EP2 subtype antibody Prostaglandin E receptor 2 subtype EP2 53kDa antibody Prostaglandin E receptor 2 subtype EP2 antibody Prostaglandin E2 receptor antibody Prostaglandin E2 receptor EP2 subtype antibody Prostanoid EP2 receptor antibody PTGER 2 antibody PTGER2 antibody

Uniprot ID :

P43116

more info or order :

Boster Immunoleader product webpage