Anti-PLD1 Antibody | Boster Immunoleader PB9380 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-PLD1 Antibody

catalog :

PB9380

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-PLD1 Antibody

Catalog Number :

PB9380

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Phospholipase D1(PLD1) detection. Tested with WB in Human;Mouse.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, mouse

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Mouse

Notes :

WB: The detection limit for PLD1 is approximately 0.1ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived human PLD1 recombinant protein (Position: M1-H330). Human PLD1 shares 91.8% and 90.9% amino acid (aa) sequence identity with mouse and rat PLD1, respectively.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

By somatic cell hybrid analysis, PLD1 is mapped to 3q26.31. This gene encodes a phosphatidylcholine-specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking. Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties. And PLD1 disrupted association of gamma-secretase protein components, independent of PLD1catalytic activity. What's more, PLD1 regulates intracellular trafficking of beta-amyloid, distinct from its effect on gamma-secretase activity.

Reference :

1. "Entrez Gene: PLD1 phospholipase D1, phosphatidylcholine-specific" 2. Colley, W. C., Altshuller, Y. M., Sue-Ling, C. K., Copeland, N. G., Gilbert, D. J., Jenkins, N. A., Branch, K. D., Tsirka, S. E., Bollag, R. J., Bollag, W. B., Frohman, M. A. Cloning and expression analysis of murine phospholipase D1. Biochem. J. 326: 745-753, 1997. 3. Park SH, Chun YH, Ryu SH, Suh PG, Kim H (February 1999). "Assignment of human PLD1 to human chromosome band 3q26 by fluorescence in situ hybridization". Cytogenet Cell Genet82 (3-4): 224.

Gene Name :

PLD1

Protein Name :

Phospholipase D1

Gene Full Name :

phospholipase D1, phosphatidylcholine-specific

Synonyms :

Choline phosphatase 1 antibody hPLD 1 antibody hPLD1 antibody Human ARF activated phosphatidylcholine specific phospholipase D1a antibody Phosphatidylcholine hydrolyzing phospholipase D1 antibody Phosphatidylcholine-hydrolyzing phospholipase D1 antibody Phospholipase D1 antibody Phospholipase D1 phosphatidylcholine specific antibody PhospholipaseD1 antibody PL D1 antibody PLD 1 antibody PLD1 antibody PLD1_HUMAN antibody

Uniprot ID :

Q13393

more info or order :

Boster Immunoleader product webpage