Boster Immunoleader

antibody

Anti-NMDAR2C Antibody

PB9374

100 ug/vial

240 USD

polyclonal

rabbit

human, rat

Anti-NMDAR2C Antibody

PB9374

Polyclonal

Rabbit IgG polyclonal antibody for Glutamate receptor ionotropic, NMDA 2C(GRIN2C) detection. Tested with WB in Human;Rat.

240 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: rat Predicted to work with: human

WB

Concentration: 0.1-0.5μg/ml; Tested Species: Rat; Predicted Species: Human

WB: The detection limit for NMDAR2C is approximately 0.1ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

E.coli-derived human NMDAR2C recombinant protein (Position: Q43-Q242). Human NMDAR2C shares 93% and 92.5% amino acid (aa) sequence identity with mouse and rat NMDAR2C, respectively.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

NMDAR2C, known as GRIN2C, is mapped to 17q25.1. Glutamate [NMDA] receptor subunit epsilon-3 is a protein that in humans is encoded by the GRIN2C gene. NMDA receptors are found in the central nervous system, are permeable to cations and have an important role in physiological processes such as learning, memory, and synaptic development. The receptor is a tetramer of different subunits (typically heterodimer of subunit 1 with one or more of subunits 2A-D), forming a channel that is permeable to calcium, potassium, and sodium, and whose properties are determined by subunit composition. Alterations in the subunit composition of the receptor are associated with pathophysiological conditions such as Parkinson's disease, Alzheimer's disease, depression, and schizophrenia. Alternative splicing results in multiple transcript variants.

1. Kalsi G, Whiting P, Bourdelles BL, Callen D, Barnard EA, Gurling H (Apr 1998). "Localization of the human NMDAR2D receptor subunit gene (GRIN2D) to 19q13.1-qter, the NMDAR2A subunit gene to 16p13.2 (GRIN2A), and the NMDAR2C subunit gene (GRIN2C) to 17q24-q25 using somatic cell hybrid and radiation hybrid mapping panels". Genomics47 (3): 423–5. doi:10.1006/geno.1997.5132.PMID 9480759. 2. "Entrez Gene: GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C".

GRIN2C

Glutamate receptor ionotropic, NMDA 2C

glutamate receptor, ionotropic, N-methyl D-aspartate 2C

GluN2C antibody Glutamate [NMDA] receptor subunit epsilon-3 antibody Glutamate Receptor Ionotropic N Methyl D Aspartate 2C antibody Glutamate receptor ionotropic, NMDA 2C antibody Glutamate receptor, ionotropic, N methyl D aspartate 2C antibody Grin2c antibody N Methly D Aspartate Receptor Channel Subunit Epsilon 3 antibody N Methyl D Aspartate Receptor Subtype 2C antibody N methyl D aspartate receptor subunit 2C antibody N-methyl D-aspartate receptor subtype 2C antibody NMDAR2C antibody NMDE3_HUMAN antibody NR2C antibody OTTHUMP00000041930 antibody

Q14957