Anti-Semaphorin 3A Antibody | Boster Immunoleader PB9353 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-Semaphorin 3A Antibody

catalog :

PB9353

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-Semaphorin 3A Antibody

Catalog Number :

PB9353

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Semaphorin-3A(SEMA3A) detection. Tested with WB in Human.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Notes :

WB: The detection limit for Semaphorin 3A is approximately 0.1ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived human Semaphorin 3A recombinant protein (Position: K550-V771). Human Semaphorin 3A shares 93% and 94% amino acid (aa) sequence identity with mouse and rat Semaphorin 3A, respectively.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

SEMA3A is also known as COLL1, SEMA1 or SEMAL. This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease.

Reference :

1. Nakano Y, et al. A nonsynonymous polymorphism in semaphorin 3A as a risk factor for human unexplained cardiac arrest with documented ventricular fibrillation. PLoS Genet, 2013 Apr. 2. Takagawa S, et al. Decreased semaphorin3A expression correlates with disease activity and histological features of rheumatoid arthritis. BMC Musculoskelet Disord, 2013 Jan 23. 3. Vadasz Z, et al. The role of B regulatory cells and Semaphorin3A in atopic diseases. Int Arch Allergy Immunol, 2014.

Gene Name :

SEMA3A

Protein Name :

Semaphorin-3A

Gene Full Name :

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A

Synonyms :

Coll 1 antibody Coll1 antibody HH16 antibody Hsema I antibody Hsema III antibody sema domain immunoglobulin domain (Ig) short basic domain secreted (semaphorin) 3A antibody Sema III antibody SEMA1 antibody SEMA1-PEN antibody SEMA3A antibody SEMAD antibody SEMAIII antibody SEMAL antibody Semaphorin 3A precursor antibody Semaphorin III antibody Semaphorin like growth cone guidance homolog of chick collapsin antibody Semaphorin-3A precursor antibody Semaphorin3A antibody SemD antibody

Uniprot ID :

Q14563

more info or order :

Boster Immunoleader product webpage