Boster Immunoleader

antibody

Anti-ERAB Antibody

PB9336

100 ug/vial

240 USD

polyclonal

rabbit

human, mouse

western blot, immunohistochemistry - paraffin section

Anti-ERAB Antibody

PB9336

Polyclonal

Rabbit IgG polyclonal antibody for 3-hydroxyacyl-CoA dehydrogenase type-2(HSD17B10) detection. Tested with WB, IHC-P in Human;Mouse.

240 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human, mouse

WB,IHC-P

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Mouse

Concentration: 0.5-1μg/ml; Tested Species: Human

WB: The detection limit for ERAB is approximately 0.1ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

E.coli-derived human ERAB recombinant protein (Position: E48-P261). Human ERAB shares 87% and 88% amino acid (aa) sequence identity with mouse and rat ERAB, respectively.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

ERAB is also known as HSD17B10 or HADH2. This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids, and is a subunit of mitochondrial ribonuclease P, which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease, and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.

1. Deutschmann AJ, et al. Mutation or knock-down of 17β-hydroxysteroid dehydrogenase type 10 cause loss of MRPP1 and impaired processing of mitochondrial heavy strand transcripts. Hum Mol Genet, 2014 Jul 1. 2. Yang SY, et al. Roles of 17β-hydroxysteroid dehydrogenase type 10 in neurodegenerative disorders. J Steroid Biochem Mol Biol, 2014 Sep.

HSD17B10

3-hydroxyacyl-CoA dehydrogenase type-2

hydroxysteroid (17-beta) dehydrogenase 10

17 beta hydroxysteroid dehydrogenase 10 antibody 17 beta hydroxysteroid dehydrogenase type 10 antibody 17-beta-HSD 10 antibody 17-beta-hydroxysteroid dehydrogenase 10 antibody 17b HSD10 antibody 3 hydroxy 2 methylbutyryl CoA dehydrogenase antibody 3 hydroxyacyl CoA dehydrogenase type 2 antibody 3 hydroxyacyl CoA dehydrogenase type II antibody 3-hydroxy-2-methylbutyryl-CoA dehydrogenase antibody 3-hydroxyacyl-CoA dehydrogenase type II antibody 3-hydroxyacyl-CoA dehydrogenase type-2 antibody AB binding alcohol dehydrogenase antibody ABAD antibody Ads9 antibody Amyloid beta binding polypeptide antibody Amyloid beta peptide binding alcohol dehydrogenase antibody Amyloid beta peptide binding protein antibody CAMR antibody DUPXp11.22 antibody Endoplasmic Reticulum Amyloid Binding Protein antibody Endoplasmic reticulum associated amyloid beta peptide binding protein antibody Endoplasmic reticulum-associated amyloid beta-peptide-binding protein antibody ER associated amyloid beta-binding protein antibody ERAB antibody HADH 2 antibody HADH2 antibody HCD 2 antibody HCD2 antibody HCD2_HUMAN antibody Hsd17b10 antibody Hydroxyacyl CoA Dehydrogenase type II antibody Hydroxyacyl Coenzyme A dehydrogenase type II antibody Hydroxysteroid (17 beta) dehydrogenase 10 antibody Mental retardation X linked syndromic 11 antibody MHBD antibody Mitochondrial L3 Hydroxyacyl CoA Dehydrogenase antibody Mitochondrial ribonuclease P protein 2 antibody Mitochondrial RNase P protein 2 antibody MRPP2 antibody MRX17 antibody SCHAD antibody SDR5C1 antibody Short chain dehydrogenase/reductase family 5C member 1 antibody Short chain L 3 hydroxyacyl CoA dehydrogenase type 2 antibody Short chain type dehydrogenase/reductase XH98G2 antibody Short-chain type dehydrogenase/reductase XH98G2 antibody Type 10 17b HSD antibody Type 10 17beta hydroxysteroid dehydrogenase antibody Type II HADH antibody XH98G2 antibody

Q99714