Boster Immunoleader

antibody

Anti-NMDAR2A Antibody

PB9335

100 ug/vial

240 USD

polyclonal

rabbit

Anti-NMDAR2A Antibody

PB9335

Polyclonal

Rabbit IgG polyclonal antibody for Glutamate receptor ionotropic, NMDA 2A(GRIN2A) detection. Tested with WB in Human;Mouse;Rat.

240 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: mouse, rat Predicted to work with: human

WB

Concentration: 0.1-0.5μg/ml; Tested Species: Mouse, Rat; Predicted Species: Human

WB: The detection limit for NMDAR2A is approximately 0.1ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

E.coli-derived human NMDAR2A recombinant protein (Position: D958-R1300). Human NMDAR2A shares 89% and 90% amino acid (aa) sequence identity with mouse and rat NMDAR2A, respectively.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

GRIN2A is also known as N-methyl-D-aspartate receptor channel, subunit epsilon-1(NMDAR2A). This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants.

1. Kalsi, G.; Whiting, P.; Le Bourdelles, B.; Callen, D.; Barnard, E. A.; Gurling, H. : Localization of the human NMDAR2D receptor subunit gene (GRIN2D) to 19q13.1-qter, the NMDAR2A subunit gene to 16p13.2 (GRIN2A), and the NMDAR2C subunit gene (GRIN2C) to 17q24-q25 using somatic cell hybrid and radiation hybrid mapping panels. Genomics 47: 423-425, 1998. 2. Micu, I.; Jiang, Q.; Coderre, E.; Ridsdale, A.; Zhang, L.; Woulfe, J.; Yin, X.; Trapp, B. D.; McRory, J. E.; Rehak, R.; Zamponi, G. W.; Wang, W.; Stys, P. K. : NMDA receptors mediate calcium accumulation in myelin during chemical ischaemia. Nature 439: 988-992, 2006.

GRIN2A

Glutamate receptor ionotropic, NMDA 2A

glutamate receptor, ionotropic, N-methyl D-aspartate 2A

Glutamate [NMDA] receptor subunit epsilon 1 antibody Glutamate [NMDA] receptor subunit epsilon-1 antibody Glutamate receptor antibody Glutamate receptor ionotropic N methyl D aspartate 2A antibody GRIN 2A antibody GRIN2A antibody HNR2A antibody N methyl D aspartate receptor channel, subunit epsilon 1 antibody N Methyl D Aspartate Receptor Subtype 2A antibody N methyl D aspartate receptor subunit 2A antibody N-methyl D-aspartate receptor subtype 2A antibody NMDA receptor subtype 2A antibody NMDA Receptor Type 2A antibody NMDAR 2A antibody NMDAR2A antibody NMDE1_HUMAN antibody NR 2A antibody NR2A antibody OTTHUMP00000160135 antibody OTTHUMP00000174531 antibody

Q12879