Boster Immunoleader

antibody

Anti-CD44 Antibody

PB9333

100 ug/vial

240 USD

polyclonal

rabbit

western blot, immunohistochemistry - paraffin section

Anti-CD44 Antibody

PB9333

Polyclonal

Rabbit IgG polyclonal antibody for CD44 antigen(CD44) detection. Tested with WB, IHC-P in Human.

240 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human

WB,IHC-P

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Concentration: 0.5-1μg/ml; Tested Species: Human

Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence at the N-terminus of human CD44(29-56aa RFAGVFHVEKNGRYSISRTEAADLCKAF), different from the related mouse and rat sequences by two amino acids.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

CD44 is also known as LHR or MC56. The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

1. Fagan-Solis KD, et al. Challenging the roles of CD44 and lipolysis stimulated lipoprotein receptor in conveying Clostridium perfringens iota toxin cytotoxicity in breast cancer. Mol Cancer, 2014 Jul 2. 2. Zhang P, et al. CD44 variant, but not standard CD44 isoforms, mediate disassembly of endothelial VE-cadherin junction on metastatic melanoma cells. FEBS Lett, 2014 Dec 20.

CD44

CD44 antigen

CD44 molecule (Indian blood group)

LHR antibody BA-1 antibody CD 44 antibody CD44 antibody CD44 antigen antibody CD44 isoform RC antibody CD44 molecule (Indian blood group) antibody CD44 molecule antibody CD44_HUMAN antibody CDw44 antibody Cell surface glycoprotein CD44 antibody chondroitin sulfate proteoglycan 8 antibody CSPG8 antibody ECM III antibody ECMR III antibody ECMR-III antibody ECMRIII antibody Epican antibody Extracellular Matrix Receptor III antibody GP90 Lymphocyte Homing Adhesion Receptor antibody GP90 lymphocyte homing/adhesion receptor antibody HCAM antibody HCELL antibody hematopoietic cell E- and L-selectin ligand antibody Heparan Sulfate Proteoglycan antibody Hermes Antigen antibody homing function and Indian blood group system antibody HSA antibody HUTCH I antibody HUTCH-I antibody HUTCH1 antibody Hyaluronate Receptor antibody IN antibody Indian blood group antibody Inlu Related p80 Glycoprotein antibody lhr antibody Ly 24 antibody MC56 antibody MDU2 antibody MDU3 antibody MGC10468 antibody MIC4 antibody MUTCH I antibody MUTCH1 antibody PGP 1 antibody PGP-1 antibody PGP-I antibody PGP1 antibody Phagocytic Glycoprotein 1 antibody Phagocytic glycoprotein I antibody Transmembrane glycoprotein antibody

P16070