Anti-PKC beta 1 Antibody | Boster Immunoleader PB9319 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-PKC beta 1 Antibody

catalog :

PB9319

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-PKC beta 1 Antibody

Catalog Number :

PB9319

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Protein kinase C beta type(PRKCB) detection. Tested with WB in Human;Mouse;Rat.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, mouse, rat

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Mouse, Rat

Notes :

WB: The detection limit for PKC beta 1 is approximately 0.1ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived human PKC beta 1 recombinant protein (Position: E542-V671). Human PKC beta 1 shares 100% amino acid (aa) sequence identity with both mouse and rat PKC beta 1.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Protein kinase C beta type is an enzyme that in humans is encoded by the PRKCB gene. It is a member of the protein kinase C (PKC) gene family. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. It has been found that PRKCB activated by oxidative conditions in the cell, induces phosphorylation of p66(SHC) and triggers mitochondrial accumulation of the protein after it is recognized by the prolyl isomerase PIN1.

Reference :

1. "Entrez Gene: PRKCB1 protein kinase C, beta 1" 2. Pinton, P., Rimessi, A., Marchi, S., Orsini, F., Migliaccio, E., Giorgio, M., Contursi, C., Minucci, S., Mantovani, F., Wieckowski, M. R., Del Sal, G., Pelicci, P. G., Rizzuto, R. Protein kinase C-beta and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66(Shc)Science 315: 659-663, 2007.

Gene Name :

PRKCB

Protein Name :

Protein kinase C beta type

Gene Full Name :

protein kinase C, beta

Synonyms :

KPCB_HUMAN antibody MGC41878 antibody PKC B antibody PKC beta antibody PKC-B antibody PKC-beta antibody PKCB antibody PRKC B antibody PRKC B1 antibody PRKCB antibody PRKCB I antibody PRKCB1 antibody PRKCB2 antibody Protein kinase C beta 1 antibody Protein kinase C beta antibody Protein kinase C beta type antibody protein kinase C, beta 1 polypeptide antibody protein kinase C, beta-1 antibody

Uniprot ID :

P05771

more info or order :

Boster Immunoleader product webpage