product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-P2X5 Antibody
catalog :
PB9305
quantity :
100 ug/vial
price :
240 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human
application :
western blot, immunohistochemistry - paraffin section
product information
Product Name :
Anti-P2X5 Antibody
Catalog Number :
PB9305
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for P2X purinoceptor 5(P2RX5) detection. Tested with WB, IHC-P in Human;Mouse;Rat.
Price :
240 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: mouse, rat Predicted to work with: human
Applications :
WB,IHC-P
Western blot :
Concentration: 0.1-0.5μg/ml; Tested Species: Rat; Predicted Species: Human
Immunohistochemistry(Paraffin-embedded S ... :
Concentration: 0.5-1μg/ml; Tested Species: Mouse, Rat; Predicted Species: Human
Notes :
WB: The detection limit for P2X5 is approximately 0.25ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
Immunogen :
E.coli-derived human P2X5 recombinant protein (Position: D333-T422). Human P2X5 shares 42% amino acid (aa) sequence identity with rat P2X5.
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).
Background :
P2X purinoceptor 5 is a protein that in humans is encoded by the P2RX5 gene. The product of this gene belongs to the family of purinoceptors for ATP. It has been identified that the P2RX5 gene within a BAC contig covering chromosome 17p13. This receptor functions as a ligand-gated ion channel. Several characteristic motifs of ATP-gated channels are present in its primary structure, but, unlike other members of the purinoceptors family, this receptor has only a single transmembrane domain. Quantitative dot blots revealed that P2X5R expression is highest in brain and immune system and is developmentally regulated.
Reference :
1. "Entrez Gene: P2RX5 purinergic receptor P2X, ligand-gated ion channel, 5" 2. Le, K.-T., Paquet, M., Nouel, D., Babinski, K., Seguela, P. Primary structure and expression of a naturally truncated human P2X ATP receptor subunit from brain and immune system. FEBS Lett. 418: 195-199, 1997. 3. Touchman, J. W., Anikster, Y., Dietrich, N. L., Maduro, V. V. B., McDowell, G., Shotelersuk, V., Bouffard, G. G., Beckstrom-Sternberg, S. M., Gahl, W. A., Green, E. D. The genomic region encompassing the nephropathic cystinosis gene (CTNS): complete sequencing of a 200-kb segment and discovery of a novel gene within the common cystinosis-causing deletion.Genome Res. 10: 165-173, 2000.
Gene Name :
P2RX5
Protein Name :
P2X purinoceptor 5
Gene Full Name :
purinergic receptor P2X, ligand gated ion channel, 5
Synonyms :
ATP receptor antibody ATP receptor subunit antibody Ionotropic ATP receptor P2X5 antibody LRH 1 antibody LRH1 antibody Lymphoid restricted histocompatibility antigen 1 antibody MGC47755 antibody P2rx5 antibody P2RX5_HUMAN antibody P2X purinoceptor 5 antibody P2X5 antibody P2X5R antibody Purinergic receptor antibody Purinergic receptor P2X ligand gated ion channel 5 antibody Purinergic receptor P2X5 antibody
Uniprot ID :
Q93086
company information
Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com
925.485.4527
headquarters: USA
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