Anti-NR5A2/LRH1 Antibody | Boster Immunoleader PB9298 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-NR5A2/LRH1 Antibody

catalog :

PB9298

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-NR5A2/LRH1 Antibody

Catalog Number :

PB9298

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Nuclear receptor subfamily 5 group A member 2(NR5A2) detection. Tested with WB in Human.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Notes :

WB: The detection limit for NR5A2 is approximately 0.25ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived human NR5A2 recombinant protein (Position: K44-R237). Human NR5A2 shares 95% amino acid (aa) sequence identity with both mouse and rat NR5A2.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

NR5A2 (nuclear receptor subfamily 5, group A, member 2) also known as liver receptor homolog-1 (LRH-1) is a protein that in humans is encoded by the NR5A2 gene. LRH-1 is a member of the nuclear receptor family of intracellulartranscription factors. LRH-1 plays a critical role in the regulation of development,cholesterol transport, bile acid homeostasis andsteroidogenesis. LRH-1 is important for maintaining pluripotence of stem cells during embryonic development. Liver receptor homolog-1 has been shown to interact with the small heterodimer partner.

Reference :

1. Goodwin, B., Jones, S. A., Price, R. R., Watson, M. A., McKee, D. D., Moore, L. B., Galardi, C., Wilson, J. G., Lewis, M. C., Roth, M. E., Maloney, P. R., Willson, T. M., Kliewer, S. A. A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis. Molec. Cell 6: 517-526, 2000. 2. Gu, P.; Goodwin, B.; Chung, A. C. -K.; Xu, X.; Wheeler, D. A.; Price, R. R.; Galardi, C.; Peng, L.; Latour, A. M.; Koller, B. H.; Gossen, J.; Kliewer, S. A.; Cooney, A. J. (2005). "Orphan Nuclear Receptor LRH-1 is Required to Maintain Oct4 Expression at the Epiblast Stage of Embryonic Development". Molecular and Cellular Biology 25(9): 3492–3505.

Gene Name :

NR5A2

Protein Name :

Nuclear receptor subfamily 5 group A member 2

Gene Full Name :

nuclear receptor subfamily 5, group A, member 2

Synonyms :

Alpha-1-fetoprotein transcription factor antibody B1-binding factor antibody B1F antibody B1F2 antibody CPF antibody CYP7A promoter-binding factor antibody FTF antibody FTZ F1 antibody FTZ F1beta antibody FTZ-F1 antibody FTZ-F1beta antibody hB1F 2 antibody HB1F antibody hB1F-2 antibody Hepatocytic transcription factor antibody Liver receptor homolog 1 antibody LRH-1 antibody LRH1 antibody Nr5a2 antibody NR5A2_HUMAN antibody Nuclear receptor subfamily 5 group A member 2 antibody

Uniprot ID :

O00482

more info or order :

Boster Immunoleader product webpage