Anti-Nurr1 Antibody | Boster Immunoleader PB9297 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-Nurr1 Antibody

catalog :

PB9297

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-Nurr1 Antibody

Catalog Number :

PB9297

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Nuclear receptor subfamily 4 group A member 2(NR4A2) detection. Tested with WB in Human.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Notes :

WB: The detection limit for Nurr1 is approximately 0.25ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived human Nurr1 recombinant protein (Position: D383-F598). Human Nurr1 shares 100% amino acid (aa) sequence identity with both mouse and rat Nurr1.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Reference :

1. Hering, R., Petrovic, S., Mietz, E.-M., Holzmann, C., Berg, D., Bauer, P., Woitalla, D., Muller, T., Berger, K., Kruger, R., Riess, O. Extended mutation analysis and association studies of Nurr1 (NR4A2) in Parkinson disease. Neurology 62: 1231-1232, 2004. 2. Law, S. W., Conneely, O. M., DeMayo, F. J., O'Malley, B. W. Identification of a new brain-specific transcription factor, NURR1. Molec. Endocr. 6: 2129-2135, 1992.

Gene Name :

NR4A2

Protein Name :

Nuclear receptor subfamily 4 group A member 2

Gene Full Name :

nuclear receptor subfamily 4, group A, member 2

Synonyms :

HZF 3 antibody HZF3 antibody Immediate-early response protein NOT antibody Intermediate early receptor protein antibody NGFI B/nur77 beta type transcription factor homolog antibody NOT antibody NR4A2 antibody NR4A2_HUMAN antibody nuclear receptor of T cells antibody nuclear receptor related 1 antibody Nuclear receptor subfamily 4 group A member 2 antibody Nur related protein 1 homolog antibody nur related protein-1, human homolog of antibody Nurr 1 antibody Orphan nuclear receptor NR4A2 antibody Orphan nuclear receptor NURR1 antibody RNR 1 antibody RNR1 antibody T cell nuclear receptor NOT antibody T-cell nuclear receptor NOT antibody TINUR antibody Transcriptionally inducible nuclear receptor antibody Transcriptionally inducible nuclear receptor related antibody Transcriptionally inducible nuclear receptor related 1 antibody Transcriptionally-inducible nuclear receptor antibody

Uniprot ID :

P43354

more info or order :

Boster Immunoleader product webpage