Boster Immunoleader

antibody

Anti-ANP Antibody

PB9295

100 ug/vial

240 USD

polyclonal

rabbit

Anti-ANP Antibody

PB9295

Polyclonal

Rabbit IgG polyclonal antibody for Natriuretic peptides A(NPPA) detection. Tested with WB in Human;Mouse;Rat.

240 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: mouse, rat Predicted to work with: human

WB

Concentration: 0.1-0.5μg/ml; Tested Species: Mouse, Rat; Predicted Species: Human

WB: The detection limit for ANP is approximately 0.25ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence at the C-terminus of human ANP(124-151aa SLRRSSCFGGRMDRIGAQSGLGCNSFRY), different from the related mouse and rat sequences by one amino acid.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Atrial natriuretic peptide (ANP), also known as NPPA or PND, is a powerful vasodilator, and a protein (polypeptide) hormone secreted by heart muscle cells. This gene is mapped to 1p36.22. It is involved in the homeostatic control of body water, sodium, potassium and fat (adipose tissue). ANP is released by muscle cells in the upper chambers (atria) of the heart (atrial myocytes) in response to high blood volume. It acts to reduce the water, sodium and adipose loads on the circulatory system, thereby reducing blood pressure. ANP has exactly the opposite function of the aldosterone secreted by the zona glomerulosa in regard to its effect on sodium in the kidney – that is, aldosterone stimulates sodium retention and it generates sodium loss.

1. Addicks K, Forssmann WG, Henkel H, Holthausen U, Menz V, Rippegather G, Ziskoven D (1989). "Calcium-calmodulin antagonists Influences the release of cardiodilatin/ANP from atrial cardiocytes". In Wambach G, Kaufmann W.Endocrinology of the heart. Berlin: Springer-Verlag. 1. 2. Potter LR, Yoder AR, Flora DR, Antos LK, Dickey DM (2009). "Natriuretic peptides: their structures, receptors, physiologic functions and therapeutic applications". Handb Exp Pharmacol. Handbook of Experimental Pharmacology 191 (191): 341–66. 3. Widmaier, Eric P.; Hershel Raff; Kevin T. Strang (2008). Vander's Human Physiology, 11th Ed. McGraw-Hill. pp. 291, 509–10.

NPPA

Natriuretic peptides A

natriuretic peptide A

ANF antibody ANF_HUMAN antibody ANP antibody ATFB6 antibody Atrial natriuretic factor antibody Atrial natriuretic factor precursor antibody Atrial natriuretic peptide antibody Atriopeptin antibody Cardionatrin antibody CDD ANF antibody CDD-ANF antibody CDP antibody Natriuretic peptide A antibody Natriuretic Peptide Precursor A antibody NPPA antibody PND antibody Prepronatriodilatin antibody

P01160