Boster Immunoleader

antibody

Anti-HEF1 Antibody

PB9289

100 ug/vial

240 USD

polyclonal

rabbit

Anti-HEF1 Antibody

PB9289

Polyclonal

Rabbit IgG polyclonal antibody for Enhancer of filamentation 1(NEDD9) detection. Tested with WB in Human.

240 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human

WB

Concentration: 0.1-0.5μg/ml; Tested Species: Human

WB: The detection limit for HEF1 is approximately 0.1ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

E.coli-derived human HEF1 recombinant protein (Position: K273-E421). Human HEF1 shares 83% amino acid (aa) sequence identity with mouse HEF1.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Enhancer of filamentation 1 (EF1), also known as NEDD-9, is a protein that in humans is encoded by the NEDD9 gene. The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. It is mapped to 6p24.2. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. NEDD9 is also a highly relevant cancer gene that governs metastatic potential in human melanoma. What’s more, it has been speculated that NEDD9 may be an important linking element between extracellular signaling and regulation of the cytoskeleton.

1. Law, S. F., Estojak, J., Wang, B., Mysliwiec, T., Kruh, G., Golemis, E. A. Human enhancer of filamentation 1, a novel p130(cas)-like docking protein, associates with focal adhesion kinase and induces pseudohyphal growth in Saccharomyces cerevisiae. Molec. Cell. Biol. 16: 3327-3337, 1996. 2. Gross, M. B. Personal Communication. Baltimore, Md. 9/4/2012.

NEDD9

Enhancer of filamentation 1

neural precursor cell expressed, developmentally down-regulated 9

CAS L antibody Cas like docking antibody Cas scaffolding protein family member 2 antibody CAS-L antibody CAS2 antibody CASL antibody CASL_HUMAN antibody CASS2 antibody Crk associated substrate related antibody Crk associated substrate related protein antibody CRK-associated substrate-related protein antibody dJ49G10.2 (Enhancer of Filamentation 1 (HEF1)) antibody dJ49G10.2 antibody dJ761I2.1 (enhancer of filamentation (HEF1)) antibody dJ761I2.1 antibody Enhancer of filamentation 1 antibody Enhancer of filamentation 1 p55 antibody HEF 1 antibody HEF1 antibody NEDD 9 antibody NEDD-9 antibody NEDD9 antibody NEDD9 protein antibody Neural cell expressed developmentally down regulated 9 antibody Neural precursor cell expressed developmentally down regulated 9 antibody Neural precursor cell expressed developmentally down-regulated protein 9 antibody NY REN 12 antigen antibody p105 antibody Protein NEDD9 antibody Renal carcinoma antigen NY-REN-12 antibody

Q14511