Boster Immunoleader

antibody

Anti-MMP14 Antibody

PB9283

100 ug/vial

240 USD

polyclonal

rabbit

Anti-MMP14 Antibody

PB9283

Polyclonal

Rabbit IgG polyclonal antibody for Matrix metalloproteinase-14(MMP14) detection. Tested with WB in Human.

240 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human

WB

Concentration: 0.1-0.5μg/ml; Tested Species: Human

WB: The detection limit for MMP14 is approximately 0.25ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence at the C-terminus of human MMP14 (557-582aa LAVFFFRRHGTPRRLLYCQRSLLDKV), different from the related mouse and rat sequences by one amino acid.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Matrix metalloproteinase-14, also called MT-MMP 1, is an enzyme that in humans is encoded by the MMP14 gene. The protein encoded by this gene is a member of the membrane-type MMP subfamily. This gene is mapped to 14q11.2. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. This gene may be involved in actin cytoskeleton reorganization by cleaving PTK7. It acts as a positive regulator of cell growth and migration via activation of MMP15.

1. Chun, T.-H., Hotary, K. B., Sabeh, F., Saltiel, A. R., Allen, E. D., Weiss, S. J. A pericellular collagenase directs the 3-dimensional development of white adipose tissue. Cell 125: 577-591, 2006. 2. Oh, J., Takahashi, R., Adachi, E., Kondo, S., Kuratomi, S., Noma, A., Alexander, D. B., Motoda, H., Okada, A., Seiki, M., Itoh, T., Itohara, S., Takahashi, C., Noda, M. Mutations in two matrix metalloproteinase genes, MMP-2, and MT1-MMP, are synthetic lethal in mice. Oncogene 23: 5041-5048, 2004. 3. Ueda, M., Yamashita, Y., Takehara, M., Terai, Y., Kumagai, K., Ueki, K., Kanda, K., Yamaguchi, H., Akise, D., Hung, Y.-C., Ueki, M. Survivin gene expression in endometriosis. J. Clin. Endocr. Metab. 87: 3452-3459, 2002.

MMP14

Matrix metalloproteinase-14

matrix metallopeptidase 14 (membrane-inserted)

Matrix metallopeptidase 14 (membrane inserted) antibody Matrix metalloproteinase 14 antibody Matrix metalloproteinase-14 antibody Membrane type 1 matrix metalloproteinase antibody Membrane type 1 metalloprotease antibody Membrane type matrix metalloproteinase 1 antibody Membrane-type matrix metalloproteinase 1 antibody Membrane-type-1 matrix metalloproteinase antibody MMP 14 antibody MMP X1 antibody MMP-14 antibody MMP-X1 antibody Mmp14 antibody MMP14_HUMAN antibody MMPX1 antibody MT MMP 1 antibody MT-MMP 1 antibody MT1 MMP antibody MT1-MMP antibody MT1MMP antibody MTMMP 1 antibody MTMMP1 antibody

P50281