Boster Immunoleader

antibody

Anti-Galectin 3 Antibody

PB9279

100 ug/vial

240 USD

polyclonal

rabbit

mouse, rat

western blot, immunohistochemistry - paraffin section

Anti-Galectin 3 Antibody

PB9279

Polyclonal

Rabbit IgG polyclonal antibody for Galectin-3(LGALS3) detection. Tested with WB, IHC-P in Mouse;Rat.

240 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: mouse, rat

WB,IHC-P

Concentration: 0.1-0.5μg/ml; Tested Species: Mouse

Concentration: 0.5-1μg/ml; Tested Species: Mouse, Rat

WB: The detection limit for Galectin 3 is approximately 0.1ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

E.coli-derived mouse Galectin 3 recombinant protein (Position: K153-I264). Mouse Galectin 3 shares 88% and 91% amino acid (aa) sequence identity with human and rat Galectin 3, respectively.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

Galectin-3(GAL3), also known as LGALS3, MAC2 or GALBP, is a member of the lectin family, of which 14 mammalian galectins have been identified. Galectin-3 is encoded by a single gene, it located on chromosome 14, locus q21–q22. It is expressed in the nucleus, cytoplasm,mitochondrion, cell surface, and extracellular space. Studies have also shown that the expression of galectin-3 is implicated in a variety of processes associated with heart failure, including myofibroblast proliferation, fibrogenesis, tissue repair, inflammation, and Ventricular remodeling. Galectin-3 is expressed in various tissues and organs, but is significantly absent in normal hepatocytes.

1. Dumic J, Dabelic S, Flögel M. (2006). "Galectin-3: an open-ended story.". BBA General Subjects 1760(4): 616–635. 2. Liu F, Patterson RJ, Wang JL. (2002). "Intracellular function of galectins.". BBA General Subjects 1572 (2-3): 263–273. 3. Cooper D. (2002). "Galectinomics: finding themes in complexity.". BBA General Subjects 1572 (2-3): 209–231. 4. Raimond J, Zimonjic DB, Mignon C, et al. (1997). "Mapping of the galectin-3 gene (LGALS3) to human chromosome 14 at region 14q21—22.". Mamm. Genome 8 (9): 706–707.

LGALS3

Galectin-3

lectin, galactoside-binding, soluble, 3

35 kDa lectin antibody Carbohydrate binding protein 35 antibody Carbohydrate-binding protein 35 antibody CBP 35 antibody CBP35 antibody GAL 3 antibody Gal-3 antibody GAL3 antibody Galactose specific lectin 3 antibody Galactose-specific lectin 3 antibody Galactoside binding protein antibody Galactoside-binding protein antibody GALBP antibody Galectin 3 internal gene,included antibody Galectin-3 antibody Galectin3 antibody GALIG antibody GBP antibody IgE binding protein antibody IgE-binding protein antibody L 31 antibody L 34 antibody L-31 antibody L-34 galactoside-binding lectin antibody L31 antibody Laminin binding protein antibody Laminin-binding protein antibody Lectin galactose binding soluble 3 antibody Lectin L 29 antibody Lectin L-29 antibody Lectin, galactose binding, soluble 3 antibody LEG3_HUMAN antibody LGALS 3 antibody LGALS2 antibody LGALS3 antibody LGALS3 protein antibody MAC 2 antigen antibody Mac-2 antibody Mac-2 antigen antibody MAC2 antibody Macrophage galactose-specific lectin antibody MGC105387 antibody

P16110