Anti-ABCB4 Antibody | Boster Immunoleader PB9275 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-ABCB4 Antibody

catalog :

PB9275

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry - paraffin section

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-ABCB4 Antibody

Catalog Number :

PB9275

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Multidrug resistance protein 3(ABCB4) detection. Tested with WB, IHC-P in Human;Mouse;Rat.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, mouse, rat

Applications :

WB,IHC-P

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Immunohistochemistry(Paraffin-embedded S ... :

Concentration: 0.5-1μg/ml; Tested Species: Human, Mouse, Rat

Notes :

WB: The detection limit for ABCB4 is approximately 0.1ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived human ABCB4 recombinant protein (Position: A601-A720). Human ABCB4 shares 79% amino acid (aa) sequence identity with both mouse and rat ABCB4.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

Background :

Adenosine triphosphate-binding cassette subfamily B, member 4 (ABCB4), also called MDR3, is a protein that in humans is encoded by the ABCB4 gene. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. The ABCB4 gene contains 28 exons and 27 of these contain coding sequences for the two homologous halves of the protein that correlate with functional domains. ABCB4 gene mutations represent a genetic factor involved in this peculiar form of cholesterol gallstone disease in adults.

Reference :

1. Lincke, C. R., Smit, J. J., van der Velde Koerts, T., Borst, P. Structure of the human MDR3 gene and physical mapping of the human MDR locus. J. Biol. Chem. 266: 5303-5310, 1991. 2. Rosmorduc, O., Hermelin, B., Poupon, R. MDR3 gene defect in adults with symptomatic intrahepatic and gallbladder cholesterol cholelithiasis. Gastroenterology 120: 1459-1467, 2001.

Gene Name :

ABCB4

Protein Name :

Multidrug resistance protein 3

Gene Full Name :

ATP-binding cassette, sub-family B (MDR/TAP), member 4

Synonyms :

ABC 21 antibody ABC B4 antibody ABC21 antibody ABCB 4 antibody Abcb4 antibody ABCB4 protein antibody ATP binding cassette sub family B MDR/TAP member 4 antibody ATP binding cassette sub family B member 4 antibody ATP-binding cassette sub-family B member 4 antibody MDR 3 antibody MDR2 antibody MDR2/3 antibody MDR3 antibody MDR3 P glycoprotein antibody MDR3 P gp antibody MDR3_HUMAN antibody Multidrug resistance protein 3 antibody Multiple drug resistance 3 antibody P glycoprotein 3 antibody P-glycoprotein 3 antibody PFIC 3 antibody PFIC3 antibody PGY 3 antibody PGY3 antibody

Uniprot ID :

P21439

more info or order :

Boster Immunoleader product webpage