Anti-TRP 7 Antibody | Boster Immunoleader PB9272 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-TRP 7 Antibody

catalog :

PB9272

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-TRP 7 Antibody

Catalog Number :

PB9272

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Short transient receptor potential channel 7(TRPC7) detection. Tested with WB in Human;Mouse.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, mouse

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Mouse

Notes :

WB: The detection limit for TRP 7 is approximately 0.2ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived human TRP 7 recombinant protein (Position: K716-I862). Human TRP 7 shares 95% amino acid (aa) sequence identity with mouse TRP 7.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Transient receptor potential cation channel, subfamily C, member 7, also known as TRPC7, is a human gene encoding a protein of the same name. Using a cosmid/BAC contig, this gene is mapped to chromosome 21q22.3. TRPC7 is the most abundantly expressed long TRPC in peripheral blood and in some blood cell lines. The protein encoded by this gene is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death.

Reference :

1. Du, J., Xie, J., Yue, L. Intracellular calcium activates TRPM2 and its alternative spliced isoforms. Proc. Nat. Acad. Sci. 106: 7239-7244, 2009. 2. Farooqi, A. A., Javeed, M. K., Javed, Z., Riaz, A. M., Mukhtar, S., Minhaj, S., Abbas, S., Bhatti, S. TRPM channels: same ballpark, different players, and different rules in immunogenetics. Immunogenetics 63: 773-787, 2011. 3. McQuillin, A., Bass, N. J., Kalsi, G., Lawrence, J., Puri, V., Choudhury, K., Detera-Wadleigh, S. D., Curtis, D., Gurling, H. M. D. Fine mapping of a susceptibility locus for bipolar and genetically related unipolar affective disorders, to a region containing the C21ORF29 and TRPM2 genes on chromosome 21q22.3. Molec. Psychiat. 11: 134-142, 2006.

Gene Name :

TRPC7

Protein Name :

Short transient receptor potential channel 7

Gene Full Name :

transient receptor potential cation channel, subfamily C, member 7

Synonyms :

Capacitative calcium channel TRPC7 antibody cation channel, subfamily C, member 7 antibody hTRP7 antibody KNP3 antibody Likley ortholog of mouse transient receptor potential cation channel subfamily C member 7 antibody mTRP7 antibody Putative capacitative calcium channel antibody Short transient receptor potential channel 7 antibody Transient receptor potential cation channel subfamily C member 7 antibody transient receptor potential-related channel 7, a novel putative Ca2+ channel protein antibody Transient receptor protein 7 antibody TRP 7 antibody TRP-7 antibody TRP7 protein antibody TRPC 7 antibody TRPC7 antibody Trpc7 transient receptor potential cation channel, subfamily C, member 7 antibody TRPC7_HUMAN antibody TRPM2 antibody Trrp8 antibody

Uniprot ID :

Q9HCX4

more info or order :

Boster Immunoleader product webpage