Anti-TRPC5 Antibody | Boster Immunoleader PB9271 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-TRPC5 Antibody

catalog :

PB9271

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot

more info or order :

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product information

Product Name :

Anti-TRPC5 Antibody

Catalog Number :

PB9271

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Short transient receptor potential channel 5(TRPC5) detection. Tested with WB in Human.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Notes :

WB: The detection limit for TRPC5 is approximately 0.2ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived human TRPC5 recombinant protein (Position: K684-L973). Human TRPC5 shares 90% amino acid (aa) sequence identity with mouse TRPC5.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Short transient receptor potential channel 5 (TrpC5), also known as TRP-5, is a protein that in humans is encoded by the TRPC5 gene. TRPC5 is subtype of the TRPC family of mammalian transient receptor potential ion channels. It is mapped to Xq23. The predicted 973-amino acid TRPC5 protein has a calculated molecular mass of 111.5 kD. It contains the characteristic 8 predicted transmembrane domains (TM1 through TM8), including a pore region (TM7) between TM6 and TM8. TRPC5 is a multi-pass membrane protein and is thought to form a receptor-activated non-selective calcium permeant cation channel, and it is a candidate for the regulation of calcium waves. The protein is active alone or as a heteromultimeric assembly with TRPC1, TRPC3, and TRPC4.

Reference :

1. "Entrez Gene: transient receptor potential cation channel" 2. Greka, A., Navarro, B., Oancea, E., Duggan, A., Clapham, D. E. TRPC5 is a regulator of hippocampal neurite length and growth cone morphology. Nature Neurosci. 6: 837-845, 2003. 3. Sossey-Alaoui, K., Lyon, J. A., Jones, L., Abidi, F. E., Hartung, A. J., Hane, B., Schwartz, C. E., Stevenson, R. E., Srivastava, A. K. Molecular cloning and characterization of TRPC5 (HTRP5), the human homologue of a mouse brain receptor-activated capacitative Ca(2+) entry channel. Genomics 60: 330-340, 1999.

Gene Name :

TRPC5

Protein Name :

Short transient receptor potential channel 5

Gene Full Name :

transient receptor potential cation channel, subfamily C, member 5

Synonyms :

Htrp 5 antibody Htrp-5 antibody Htrp5 antibody Short transient receptor potential channel 5 antibody Transient receptor potential cation channel subfamily C member 5 antibody Transient receptor potential channel 5 antibody Transient receptor protein 5 antibody TRP 5 antibody TRP-5 antibody TRP5 antibody TRPC 5 antibody TrpC5 antibody TRPC5_HUMAN antibody

Uniprot ID :

Q9UL62

more info or order :

Boster Immunoleader product webpage