Anti-Kallikrein 4 Antibody | Boster Immunoleader PB9260 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-Kallikrein 4 Antibody

catalog :

PB9260

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-Kallikrein 4 Antibody

Catalog Number :

PB9260

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Kallikrein-4(KLK4) detection. Tested with WB in Human.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Notes :

WB: The detection limit for Kallikrein 4 is approximately 0.25ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived human Kallikrein 4 recombinant protein (Position: I31-S254).

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Kallikrein-related peptidase 4, also known as PSTS or EMSP1, is a protein which in humans is encoded by the KLK4 gene. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. In particular, they may serve as biomarkers for both prostate cancer and breast cancer. It has been found that KLK4 is a proliferative factor with effects on gene expression and it may have a role in prostate cancer development and progression.

Reference :

1. Klokk, T. I., Kilander, A., Xi, Z., Waehre, H., Risberg, B., Danielson, H. E., Saatcioglu, F. Kallikrein 4 is a proliferative factor that is overexpressed in prostate cancer. Cancer Res. 67: 5221-5230, 2007. 2. Nelson PS, Gan L, Ferguson C, Moss P, Gelinas R, Hood L, Wang K (March 1999). 3. Simmer JP, Fukae M, Tanabe T, Yamakoshi Y, Uchida T, Xue J, Margolis HC, Shimizu M, DeHart BC, Hu CC, Bartlett JD (June 2000).

Gene Name :

KLK4

Protein Name :

Kallikrein-4

Gene Full Name :

kallikrein-related peptidase 4

Synonyms :

7S nerve growth factor alpha chain antibody AI2A1 antibody Alpha-NGF antibody Androgen-regulated message 1 antibody ARM1 antibody EC 3.4.21.- antibody EMSP 1 antibody EMSP antibody EMSP1 antibody Enamel Matrix Serine Protease 1 antibody Enamel matrix serine proteinase 1 antibody HK4 antibody Kallikrein 1-related peptidase-like b4 antibody Kallikrein 4 (prostase, enamel matrix, prostate) antibody Kallikrein 4 antibody Kallikrein antibody Kallikrein L1 antibody Kallikrein like protein 1 antibody Kallikrein related-peptidase 4 (prostase, enamel matrix, prostate) antibody Kallikrein-4 antibody Kallikrein-like protein 1 antibody Kallikrein-related peptidase 4 antibody KLK 4 antibody KLK L1 antibody KLK-L1 antibody KLK4 antibody KLK4_HUMAN antibody MGC116827 antibody MGC116828 antibody Prostase antibody Protease Serine 17 antibody PRSS 17 antibody PRSS17 antibody PSTS antibody Serine protease 17 antibody

Uniprot ID :

Q9Y5K2

more info or order :

Boster Immunoleader product webpage