Anti-PSA Antibody | Boster Immunoleader PB9259 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-PSA Antibody

catalog :

PB9259

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-PSA Antibody

Catalog Number :

PB9259

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Prostate-specific antigen(KLK3) detection. Tested with WB in Human;Rat.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, rat

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat

Notes :

WB: The detection limit for PSA is approximately 0.2ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived human PSA recombinant protein (Position: I25-P261). Human PSA shares 54% amino acid (aa) sequence identity with rat PSA.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. KLK3 is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. This gene is mapped to 19q13.33. KLK3 is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. KLK3 is produced for the ejaculate where it liquifies the semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving the cervical mucous cap, allowing the entry of sperm. It is not a unique indicator of prostate cancer, but may also detect prostatitis or benign prostatic hyperplasia.

Reference :

1. Balk SP, Ko YJ, Bubley GJ (January 2003). "Biology of prostate-specific antigen". J. Clin. Oncol. 21 (2): 383–91. 2. Catalona, W. J.; Richie, J. P.; Ahmann, F. R.; Hudson, M. A.; Scardino, P. T.; Flanigan, R. C.; Dekernion, J. B.; Ratliff, T. L.; Kavoussi, L. R.; Dalkin, B. L. (1994). "Comparison of digital rectal examination and serum prostate specific antigen in the early detection of prostate cancer: Results of a multicenter clinical trial of 6,630 men". The Journal of urology 151 (5): 1283–1290. 3. Lilja H (November 2003). "Biology of prostate-specific antigen". Urology 62 (5 Suppl 1): 27–33. doi:10.1016/S0090-4295(03)00775-1.

Gene Name :

KLK3

Protein Name :

Prostate-specific antigen

Gene Full Name :

kallikrein-related peptidase 3

Synonyms :

antigen, prostate-specific antibody APS antibody Gamma seminoprotein antibody Gamma-seminoprotein antibody hK3 antibody Kallikrein 3 antibody Kallikrein 3, (prostate specific antigen) antibody Kallikrein related peptidase 3 antibody Kallikrein-3 antibody KLK 3 antibody KLK2A1 antibody KLK3 antibody KLK3_HUMAN antibody P 30 antigen antibody P-30 antigen antibody P30 antigen antibody Prostate Specific Antigen antibody Prostate-specific antigen antibody PSA antibody Semenogelase antibody Seminin antibody

Uniprot ID :

P07288

more info or order :

Boster Immunoleader product webpage