product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-CD86 Antibody
catalog :
PB9251
quantity :
100 ug/vial
price :
240 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human
application :
western blot
product information
Product Name :
Anti-CD86 Antibody
Catalog Number :
PB9251
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for T-lymphocyte activation antigen CD86(CD86) detection. Tested with WB in Human.
Price :
240 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: human
Applications :
WB
Western blot :
Concentration: 0.1-0.5μg/ml; Tested Species: Human
Notes :
WB: The detection limit for CD86 is approximately 0.25ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Immunogen :
E.coli-derived human CD86 recombinant protein (Position: A24-F329). Human CD86 shares 50% amino acid (aa) sequence identity with mouse CD86.
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.
Background :
Cluster of Differentiation 86 (also known as CD86 and B7-2) is a protein expressed on antigen-presenting cells that provides costimulatory signals necessary for T cell activation and survival. The CD86 gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. Using fluorescence in situ hybridization mapping, the CD86, like CD80, was mapped to human 3q21. The antigen presentation coactivators B71 and B72, which are important in other immune-mediated thyroid diseases, are important for lymphocytic infiltration and the immune response against thyroid carcinoma.
Reference :
1. Chen C, Gault A, Shen L, Nabavi N (May 1994). "Molecular cloning and expression of early T cell costimulatory molecule-1 and its characterization as B7-2 molecule". J. Immunol. 152 (10): 4929–36. 2. Reeves, R. H., Patch, D., Sharpe, A. H., Borriello, F., Freeman, G. J., Edelhoff, S., Disteche, C. The costimulatory genes Cd80 and Cd86 are linked on mouse chromosome 16 and human chromosome 3. Mammalian Genome 8: 581-582, 1997. 3. Shah, R., Banks, K., Patel, A., Dogra, S., Terrell, R., Powers, P. A., Fenton, C., Dinauer, C. A., Tuttle, R. M., Francis, G. L. Intense expression of the B7-2 antigen presentation coactivator is an unfavorable prognostic indicator for differentiated thyroid carcinoma of children and adolescents. J. Clin. Endocr. Metab. 87: 4391-4397, 2002.
Gene Name :
CD86
Protein Name :
T-lymphocyte activation antigen CD86
Gene Full Name :
CD86 molecule
Synonyms :
Activation B7 2 antigen antibody Activation B7-2 antigen 3 antibody Activation B7-2 antigen antibody Activation B72 antigen antibody B lymphocyte activation antigen B7 2 antibody B lymphocyte activation antigen B72 antibody B-lymphocyte activation antigen B7-2 2 antibody B-lymphocyte activation antigen B7-2 antibody B7 2 antibody B7 2 antigen antibody B7 antibody B7-2 antibody B7.2 antibody B70 antibody B72 antigen antibody BU63 antibody CD 86 antibody CD28 antigen ligand 2 2 antibody CD28 antigen ligand 2 antibody Cd28l2 antibody CD28LG2 antibody CD86 antibody CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) 1, 2 antibody CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) antibody CD86 antigen antibody CD86 molecule antibody CD86_HUMAN antibody CLS1 antibody CTLA 4 counter receptor B7 2 antibody CTLA 4 counter receptor B7.2 antibody CTLA-4 counter-receptor B7.2 2, 3 antibody CTLA-4 counter-receptor B7.2 antibody CTLA4 counter receptor B72 antibody Early T-cell costimulatory molecule 1 antibody ETC-1 antibody FUN 1 antibody FUN-1 antibody FUN1 antibody LAB72 antibody Ly-58 antibody Ly58 antibody MB7 antibody MB7-2 antibody Membrane glycoprotein antibody MGC34413 antibody T lymphocyte activation antigen CD86 antibody T-lymphocyte activation antigen CD86 antibody TS/A-2 antibody
Uniprot ID :
P42081
company information
Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com
925.485.4527
headquarters: USA
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