Anti-CD63 Antibody | Boster Immunoleader PB9250 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-CD63 Antibody

catalog :

PB9250

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot, immunohistochemistry - paraffin section

publications citing this reagent :

DU H, Dong L, Zhao B, Fu J, Wang Q, Chen F, et al. Immunostimulatory and anti-neoplasm effects of a novel palindrome CpG oligodeoxynucleotide in mice. Acta Pharmacol Sin. 2012;33:1047-54 pubmed publisher

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-CD63 Antibody

Catalog Number :

PB9250

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for CD63 antigen(CD63) detection. Tested with WB, IHC-P in Human.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

WB,IHC-P

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Immunohistochemistry(Paraffin-embedded S ... :

Concentration: 0.5-1μg/ml; Tested Species: Human

Notes :

WB: The detection limit for CD63 is approximately 0.25ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived human CD63 recombinant protein (Position: E97-M238). Human CD63 shares 74% and 73% amino acid (aa) sequence identity with mouse and rat CD63, respectively.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

Background :

CD63 antigen is a protein that in humans is encoded by the CD63 gene. The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. It is mapped to 12q13.2. CD63 is mainly associated with membranes of intracellular vesicles, although cell surface expression may be induced. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression.

Reference :

1. "Entrez Gene: CD63 CD63 molecule" 2. Gwynn, B., Eicher, E. M., Peters, L. L. Genetic localization of Cd63, a member of the transmembrane 4 superfamily, reveals two distinct loci in the mouse genome. Genomics 35: 389-391, 1996.

Gene Name :

CD63

Protein Name :

CD63 antigen

Gene Full Name :

CD63 molecule

Synonyms :

Lysosomal associated membrane protein 3 antibody CD 63 antibody CD63 antibody CD63 antigen (melanoma 1 antigen) antibody CD63 antigen antibody CD63 antigen melanoma 1 antigen antibody CD63 molecule antibody CD63_HUMAN antibody gp55 antibody granulophysin antibody LAMP 3 antibody LAMP-3 antibody LAMP3 antibody LIMP antibody Lysosomal-associated membrane protein 3 antibody lysosome associated membrane glycoprotein 3 antibody Mast cell antigen AD1 antibody ME491 antibody melanoma 1 antigen antibody Melanoma associated antigen ME491 antibody Melanoma associated antigen MLA1 antibody Melanoma-associated antigen ME491 antibody MGC72893 antibody MLA 1 antibody MLA1 antibody NGA antibody ocular melanoma associated antigen antibody Ocular melanoma-associated antigen antibody OMA81H antibody PTLGP40 antibody Tetraspanin 30 antibody Tetraspanin-30 antibody Tspan 30 antibody Tspan-30 antibody TSPAN30 antibody

Uniprot ID :

P08962

more info or order :

Boster Immunoleader product webpage