product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-CD147 Antibody
catalog :
PB9247
quantity :
100 ug/vial
price :
240 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human
application :
western blot
product information
Product Name :
Anti-CD147 Antibody
Catalog Number :
PB9247
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for Basigin(BSG) detection. Tested with WB in Human.
Price :
240 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: human
Applications :
WB
Western blot :
Concentration: 0.1-0.5μg/ml; Tested Species: Human
Notes :
WB: The detection limit for CD147 is approximately 0.2ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Immunogen :
E.coli-derived human CD147 recombinant protein (Position: E53-S385). Human CD147 shares 64% and 65% amino acid (aa) sequence identity with mouse and rat CD147, respectively.
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.
Background :
Emmprin, extracellular matrix metalloproteinase inducer, also known as Emmprin (BSG) or cluster of differentiation 147 (CD147) is a protein that in humans is encoded by the Emmprin gene. The human BSG gene is mapped to 19p13.3. This protein is a determinant for the Ok blood group system. BSG has been shown to be an essential receptor on red blood cells for the malaria parasite. It is a member of the immunoglobulin superfamily, with a structure related to the putative primordial form of the family. As members of the immunoglobulin superfamily, it plays fundamental roles in intercellular recognition involved in various immunologic phenomena, differentiation, and development. BSG is thought also to play a role in intercellular recognition. It also regulates several distinct functions, such as spermatogenesis, expression of the monocarboxylate transporter and the responsiveness of lymphocytes. BSG is a type I integral membrane receptor that has many ligands, including the cyclophilin (CyP) proteins Cyp-A and CyP-B and certain integrins. It is expressed by many cell types, including epithelial cells, endothelial cells and leukocytes.
Reference :
1. Guo, H., Majmudar, G., Jensen, T. C., Biswas, C., Toole, B. P., Gordon, M. K.Characterization of the gene for human EMMPRIN, a tumor cell surface inducer of matrix metalloproteinases.Gene 220: 99-108, 1998. 2. Zhou, S., Zhou, H., Walian, P. J., Jap, B. K.CD147 is a regulatory subunit of the gamma-secretase complex in Alzheimer's disease amyloid beta-peptide production.
Gene Name :
BSG
Protein Name :
Basigin
Gene Full Name :
basigin (Ok blood group)
Synonyms :
5A11 antigen antibody 5F7 antibody BASI_HUMAN antibody Basigin (Ok blood group) antibody Basigin antibody Blood brain barrier HT7 antigen antibody BSG antibody CD 147 antibody CD147 antibody CD147 antigen antibody Collagenase stimulatory factor antibody Emmprin antibody Extracellular matrix metalloproteinase inducer antibody Leukocyte activation antigen M6 antibody M 6 antibody M6 antibody M6 leukocyte activation antigen antibody Neurothelin antibody OK antibody OK blood group antibody OK blood group antigen antibody TCSF antibody Tumor cell derived collagenase stimulatory factor antibody Tumor cell-derived collagenase stimulatory factor antibody
Uniprot ID :
P35613
company information
Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com
925.485.4527
headquarters: USA
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