Anti-Galectin 1 Antibody | Boster Immunoleader PB9240 product information

product summary

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company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-Galectin 1 Antibody

catalog :

PB9240

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

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product information

Availability :

info changed 20150330

Product Name :

Anti-Galectin 1 Antibody

Catalog Number :

PB9240

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Galectin-1(LGALS1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human;Mouse;Rat.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, mouse, rat

Applications :

WB,IHC-P,IHC-F,ICC

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat

Immunohistochemistry(Paraffin-embedded S ... :

Concentration: 0.5-1μg/ml; Tested Species: Human, Mouse, Rat

Immunohistochemistry(Frozen Section) :

Concentration: 0.5-1μg/ml; Tested Species: Human, Rat

Immunocytochemistry :

Concentration: 0.5-1μg/ml; Tested Species: Human, Rat

Notes :

WB: The detection limit for Galectin 1 is approximately 0.2ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived human Galectin 1 recombinant protein (Position: A2-D135). Human Galectin 1 shares 88% and 90% amino acid (aa) sequences identity with mouse and rat Galectin 1, respectively.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P), IHC(F) and ICC.

Background :

Galectin-1 is a protein that in humans is encoded by the LGALS1 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-1 may act as an autocrine negative growth factor that regulates cell proliferation. Galectin-1 expression in Hodgkin Lymphoma has also been shown to mediate immunosuppression of CD8+ T-cells. It is thought to play a role in creating immune tolerance in pregnancy. It has been found that Galectin-1-mediated production of IL6 may assist in augmenting the innate immune response against NiV. Galectin-1 may also be a significant factor that augments the efficiency of the HIV-1 infection process.

Reference :

1. Das, K., Lin, Y., Widen, E., Zhang, Y., Scherer, P. E. Chromosomal localization, expression pattern, and promoter analysis of the mouse gene encoding adipocyte-specific secretory protein Acrp30. Biochem. Biophys. Res. Commun. 280: 1120-1129, 2001. 2. Schaffler, A., Orso, E., Palitzsch, K.-D., Buchler, C., Drobnik, W., Furst, A., Scholmerich, J., Schmitz, G. The human apM-1, an adipocyte-specific gene linked to the family of TNF's and to genes expressed in activated T cells, is mapped to chromosome 1q21.3-q23, a susceptibility locus identified for familial combined hyperlipidaemia (FCH). Biochem. Biophys. Res. Commun. 260: 416-425, 1999.

Gene Name :

LGALS1

Protein Name :

Galectin-1

Gene Full Name :

lectin, galactoside-binding, soluble, 1

Synonyms :

14 kDa laminin-binding protein antibody 14 kDa lectin antibody Beta galactoside binding lectin antibody Beta galactoside binding lectin L 14 I antibody beta galactoside binding protein antibody Beta-galactoside-binding lectin L-14-I antibody DKFZp686E23103 antibody Gal 1 antibody Gal-1 antibody GAL1 antibody Galaptin antibody Galbp antibody Galectin antibody Galectin-1 antibody Galectin1 antibody GBP antibody HBL antibody HLBP14 antibody HPL antibody L 14.5 antibody L-14.5 antibody L14 antibody Lactose binding lectin 1 antibody Lactose-binding lectin 1 antibody Lect14 antibody Lectin galactoside binding soluble 1 antibody Lectin galactoside-binding soluble 1 antibody LEG1_HUMAN antibody LGALS 1 antibody LGALS1 antibody Lgals1 lectin galactose binding soluble 1 antibody MAPK activating protein MP12 antibody Putative MAPK activating protein MP12 antibody Putative MAPK-activating protein PM12 antibody S Lac lectin 1 antibody S-Lac lectin 1 antibody

Uniprot ID :

P09382

more info or order :

Boster Immunoleader product webpage