Boster Immunoleader

antibody

Anti-KLF6 Antibody

PB9231

100 ug/vial

240 USD

polyclonal

rabbit

human, rat

Anti-KLF6 Antibody

PB9231

Polyclonal

Rabbit IgG polyclonal antibody for Krueppel-like factor 6(KLF6) detection. Tested with WB in Human;Rat.

240 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human, rat

WB

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat

WB: The detection limit for KLF6 is approximately 0.25ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

E.coli-derived human KLF6 recombinant protein (Position: E38-N205). Human KLF6 shares 92% and 90% amino acid (aa) sequences identity with mouse and rat KLF6, respectively.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Krueppel-like factor 6 (KLF6) is a protein that in humans is encoded by the KLF6 gene. It is a tumor suppressor gene which is located on 10p15.1. This gene encodes a nuclear protein that has three zinc fingers at the end of its C-terminal domain, a serine/threonine-rich central region, and an acidic domain lying within the N-terminal region. The zinc fingers of this protein are responsible for the specific DNA binding with the guanine-rich core promoter elements. The central region might be involved in activation or posttranslational regulatory pathways, and the acidic N-terminal domain might play an important role in the process of transcriptional activation. It is capable of activating transcription approximately 4-fold either on homologous or heterologous promoters. The DNA binding and transcriptional activity of this protein, in conjunction with its expression pattern, suggests that this protein may participate in the regulation and/or maintenance of the basal expression of pregnancy-specific glycoprotein genes and possibly other TATA box-less genes.

1. Onyango P, Koritschoner NP, Patrito LC, Zenke M, Weith A (Apr 1998). "Assignment of the gene encoding the core promoter element binding protein (COPEB) to human chromosome 10p15 by somatic hybrid analysis and fluorescence in situ hybridization". Genomics 48 (1): 143–4. 2. Li D; Yea S; Dolios G et al. (October 2005). "Regulation of Kruppel-like factor 6 tumor suppressor activity by acetylation". Cancer Res. 65 (20): 9216–25. 3. "Entrez Gene: KLF6 Kruppel-like factor 6

KLF6

Krueppel-like factor 6

Kruppel-like factor 6

B cell derived protein 1 antibody B cell-derived 1 antibody B-cell-derived protein 1 antibody BCD1 antibody CBA1 antibody COPEB antibody Core promoter element-binding protein antibody CPBP antibody GBF antibody GC rich binding factor antibody GC rich sites binding factor GBF antibody GC-rich sites-binding factor GBF antibody Klf6 antibody KLF6_HUMAN antibody Krueppel-like factor 6 antibody Krueppel-like factor 6 isoform C antibody Kruppel like zinc finger protein Zf9 antibody PAC1 antibody Proto-oncogene BCD1 antibody Protooncogene B cell derived 1 antibody ST12 antibody Suppression of tumorigenicity 12 (prostate) antibody Suppressor of tumorigenicity 12 protein antibody Transcription factor Zf9 antibody Zf9 antibody

Q99612