Boster Immunoleader

antibody

Anti-MCAK Antibody

PB9230

100 ug/vial

240 USD

polyclonal

rabbit

human, mouse, rat

western blot, immunohistochemistry - paraffin section

Anti-MCAK Antibody

PB9230

Polyclonal

Rabbit IgG polyclonal antibody for Kinesin-like protein KIF2C(KIF2C) detection. Tested with WB, IHC-P in Human;Mouse;Rat.

240 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human, mouse, rat

WB,IHC-P

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Mouse

Concentration: 0.5-1μg/ml; Tested Species: Mouse, Rat; Predicted Species: Human

WB: The detection limit for MCAK is approximately 0.25ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

E.coli-derived human MCAK recombinant protein (Position: G531-Q725). Human MCAK shares 87% amino acid (aa) sequence identity with both mouse and rat MCAK.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

Kinesin-like protein KIF2C is a protein that in humans is encoded by the KIF2C gene. It is mapped to 1p34.1. The protein encoded by this gene is a member of kinesin-like protein family. Most proteins of this family are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein acts to regulate microtubule dynamics in cells and is important for anaphase chromosome segregation and may be required to coordinate the onset of sister centromere separation. KIF2C uses microtubule depolymerizing activity to correct improper microtubule attachments at kinetochores.

1. Manning, A. L., Ganem, N. J., Bakhoum, S. F., Wagenbach, M., Wordeman, L., Compton, D. A. The kinesin-13 proteins, Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells. Molec. Biol. Cell 18: 2970-2979, 2007. 2. Kim IG, Jun DY, Sohn U, Kim YH (Feb 1998). "Cloning and expression of human mitotic centromere-associated kinesin gene". Biochim Biophys Acta 1359 (3): 181–6. 3. "Entrez Gene: KIF2C kinesin family member 2C

KIF2C

Kinesin-like protein KIF2C

kinesin family member 2C

4930402F02Rik antibody ESTM5 antibody KIF 2C antibody kif2c antibody KIF2C_HUMAN antibody Kinesein Family Member 2C antibody Kinesin family member 2C antibody kinesin like 6 (mitotic centromere associated kinesin) antibody Kinesin like 6 antibody Kinesin like protein 6 antibody Kinesin like protein KIF2C antibody Kinesin-like protein 6 antibody Kinesin-like protein KIF2C antibody KNS L6 antibody KNSL 6 antibody KNSL6 antibody MCAK antibody MGC11883 antibody Mitotic centromere associated kinesin antibody Mitotic centromere-associated kinesin antibody OTTHUMP00000010066 antibody X83316 antibody

Q99661