Boster Immunoleader

antibody

Anti-HNF1 Antibody

PB9214

100 ug/vial

240 USD

polyclonal

rabbit

human, rat

Anti-HNF1 Antibody

PB9214

Polyclonal

Rabbit IgG polyclonal antibody for Hepatocyte nuclear factor 1-alpha(HNF1A) detection. Tested with WB in Human;Rat.

240 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human, rat

WB

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat

WB: The detection limit for HNF1 is approximately 0.25ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

E.coli-derived human HNF1 recombinant protein (Position: A431-Q631). Human HNF1 shares 93% and 92% amino acid (aa) sequences identity with mouse and rat HNF1, respectively.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

HNF1 homeobox A (hepatocyte nuclear factor 1 homeobox A), also known as HNF1A or TCF1, is a human gene. It is mapped to chromosome 12q24.3. The protein encoded by this gene is a transcription factor that is highly expressed in the liver and is involved in the regulation of the expression of several liver-specific genes. HNF1A can function as a dimer. What’s more, deletion of the HNF1A activation domains or interruption of the HNF1-binding sites in the LCT promoter resulted in complete loss of transcriptional activity.

1. Courtois, G., Morgan, J. G., Campbell, L. A., Fourel, G., Crabtree, G. R. Interaction of a liver-specific nuclear factor with the fibrinogen and alpha-1-antitrypsin promoters. Science 238: 688-692, 1987. 2. Szpirer C, Riviere M, Cortese R, Nakamura T, Islam MQ, Levan G, Szpirer J (June 1992). "Chromosomal localization in man and rat of the genes encoding the liver-enriched transcription factors C/EBP, DBP, and HNF1/LFB-1 (CEBP, DBP, and transcription factor 1, TCF1, respectively) and of the hepatocyte growth factor/scatter factor gene (HGF)". Genomics 13 (2): 293–300. 3. Vaxillaire M, Boccio V, Philippi A, Vigouroux C, Terwilliger J, Passa P, Beckmann JS, Velho G, Lathrop GM, Froguel P (April 1995). "A gene for maturity onset diabetes of the young (MODY) maps to chromosome 12q". Nat. Genet. 9 (4): 418–23.

HNF1A

Hepatocyte nuclear factor 1-alpha

HNF1 homeobox A

Albumin proximal factor antibody Hepatic nuclear factor 1 alpha antibody Hepatic nuclear factor 1 antibody Hepatic transcription factor 1 alpha antibody Hepatic transcription factor 1 antibody Hepatocyte nuclear factor 1-alpha antibody HNF 1 antibody HNF 1A antibody HNF-1-alpha antibody HNF-1A antibody HNF1A antibody HNF1A_HUMAN antibody Interferon production regulator factor antibody LF B1 antibody LF B1 hepatic nuclear factor antibody LFB 1 antibody LFB1 antibody LFB1 hepatic nuclear factor antibody Liver specific transcription factor LF B1 antibody Liver specific transcription factor LFB1 antibody Liver-specific transcription factor LF-B1 antibody Maturity onset diabetes of the young 3 antibody MODY 3 antibody MODY3 antibody TCF 1 antibody TCF-1 antibody TCF1 antibody Transcription factor 1 antibody Transcription factor 1 hepatic antibody

P20823