Anti-GRIK1 Antibody | Boster Immunoleader PB9208 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-GRIK1 Antibody

catalog :

PB9208

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-GRIK1 Antibody

Catalog Number :

PB9208

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Glutamate receptor ionotropic, kainate 1(GRIK1) detection. Tested with WB in Human;Mouse;Rat.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, mouse, rat

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Mouse, Rat

Notes :

WB: The detection limit for GRIK1 is approximately 0.2ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived human GRIK1 recombinant protein (Position: R271-I450). Human GRIK1 shares 88% and 94% amino acid (aa) sequences identity with mouse and rat GRIK1, respectively.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Glutamate receptor, ionotropic, kainate 1, also known as GLUR5, is a protein that in humans is encoded by the GRIK1 gene. It is mapped to 21q21.3. This gene encodes one of the many ionotropic glutamate receptor (GluR) subunits that function as a ligand-gated ion channel. The specific GluR subunit encoded by this gene is of the kainate receptor subtype. Receptor assembly and intracellular trafficking of ionotropic glutamate receptors are regulated by RNA editing and alternative splicing. These receptors mediate excitatory neurotransmission and are critical for normal synaptic function. Exons of this gene are interspersed with exons from the C21or f41 gene, which is transcribed in the same orientation as this gene but does not seem to encode a protein.

Reference :

1. "Entrez Gene: GRIK1 glutamate receptor, ionotropic, kainate 1" 2. Eubanks, J. H., Puranam, R. S., Kleckner, N. W., Bettler, B., Heinemann, S. F., McNamara, J. O. The gene encoding the glutamate receptor subunit GluR5 is located on human chromosome 21q21.1-22.1 in the vicinity of the gene for familial amyotrophic lateral sclerosis. Proc. Nat. Acad. Sci. 90: 178-182, 1993.

Gene Name :

GRIK1

Protein Name :

Glutamate receptor ionotropic, kainate 1

Gene Full Name :

glutamate receptor, ionotropic, kainate 1

Synonyms :

EAA3 antibody EEA3 antibody Excitatory amino acid receptor 3 antibody GLR5 antibody GluR-5 antibody GluR5 antibody GluR6 antibody GluR7 antibody Glutamate receptor 5 antibody Glutamate receptor antibody Glutamate receptor ionotropic kainate 1 antibody GRIK1 antibody GRIK1_HUMAN antibody Human glutamate receptor GLUR5 antibody ionotropic kainate 1 antibody OTTHUMP00000096569 antibody

Uniprot ID :

P39086

more info or order :

Boster Immunoleader product webpage