Anti-GRIA4 Antibody | Boster Immunoleader PB9207 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-GRIA4 Antibody

catalog :

PB9207

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-GRIA4 Antibody

Catalog Number :

PB9207

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Glutamate receptor 4(GRIA4) detection. Tested with WB in Human;Mouse;Rat.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: mouse, rat Predicted to work with: human

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Mouse, Rat; Predicted Species: Human

Notes :

WB: The detection limit for GRIA4 is approximately 0.25ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived human GRIA4 recombinant protein (Position: Q176-K350). Human GRIA4 shares 99% amino acid (aa) sequence identity with both mouse and rat GRIA4.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Glutamate receptor 4 also named GRIA4 or GLUR4, is a protein that in humans is encoded by the GRIA4 gene. It is mapped to 11q22.3. This gene is a member of a family of L-glutamate-gated ion channels that mediate fast synaptic excitatory neurotransmission. These channels are also responsive to the glutamate agonist, alpha-amino-3-hydroxy-5-methyl-4-isoxazolpropionate (AMPA). Some haplotypes of this gene show a positive association with schizophrenia. What's more, glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels.

Reference :

1. "Entrez Gene: GRIA4 glutamate receptor, ionotrophic, AMPA 4" 2. Sommer, B., Keinanen, K., Verdoorn, T. A., Wisden, W., Burnashev, N., Herb, A., Kohler, M., Takagi, T., Sakmann, B., Seeburg, P. H. Flip and flop: a cell-specific functional switch in glutamate-operated channels of the CNS. Science 249: 1580-1585, 1990.

Gene Name :

GRIA4

Protein Name :

Glutamate receptor 4

Gene Full Name :

glutamate receptor, ionotropic, AMPA 4

Synonyms :

AMPA 4 antibody AMPA selective glutamate receptor 4 antibody AMPA-selective glutamate receptor 4 antibody AMPA4 antibody GluA 4 antibody GluA4 antibody GluR 4 antibody GluR D antibody GluR-4 antibody GluR-D antibody GluR4 antibody GLUR4C antibody GLURD antibody Glutamate receptor 4 antibody Glutamate receptor ionotrophic AMPA 4 antibody Glutamate receptor ionotropic antibody GRIA 4 antibody Gria4 antibody GRIA4_HUMAN antibody

Uniprot ID :

P48058

more info or order :

Boster Immunoleader product webpage