product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-GATA5 Antibody
catalog :
PB9200
quantity :
100 ug/vial
price :
240 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human, rat
application :
western blot
product information
Product Name :
Anti-GATA5 Antibody
Catalog Number :
PB9200
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for Transcription factor GATA-5(GATA5) detection. Tested with WB in Human;Rat.
Price :
240 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: rat Predicted to work with: human
Applications :
WB
Western blot :
Concentration: 0.1-0.5μg/ml; Tested Species: Rat; Predicted Species: Human
Notes :
WB: The detection limit for GATA5 is approximately 0.25ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Immunogen :
E.coli-derived human GATA5 recombinant protein (Position: M1-A397). Human GATA5 shares 75% amino acid (aa) sequence identity with mouse GATA5.
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.
Background :
Transcription factor GATA-5, also named GATAS or GATA5, is a protein that in humans is encoded by the GATA5 gene. It is mapped to 20q13.33. The protein encoded by this gene is a transcription factor that contains two GATA-type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha), and this interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity. In addition, the expression of GATA5 increased in a human colon cancer cell line within 2 hours of exposure to sodium butyrate, which induces differentiation.
Reference :
1. Gao, X., Sedgwick, T., Shi, Y.-B., Evans, T. Distinct functions are implicated for the GATA-4, -5, and -6 transcription factors in the regulation of intestine epithelial cell differentiation. Molec. Cell. Biol. 18: 2901-2911, 1998. 2. "Entrez Gene: GATA5 GATA binding protein 5
Gene Name :
GATA5
Protein Name :
Transcription factor GATA-5
Gene Full Name :
GATA binding protein 5
Synonyms :
GATA binding protein 5 antibody GATA-binding factor 5 antibody GATA5 antibody GATA5_HUMAN antibody Transcription factor GATA-5 antibody bB379O24.1 antibody GATAS antibody
Uniprot ID :
Q9BWX5
company information
Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com
925.485.4527
headquarters: USA
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