Anti-GATA3 Antibody | Boster Immunoleader PB9199 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-GATA3 Antibody

catalog :

PB9199

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, rat

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-GATA3 Antibody

Catalog Number :

PB9199

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Trans-acting T-cell-specific transcription factor GATA-3(GATA3) detection. Tested with WB in Human;Rat.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, rat

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat

Notes :

WB: The detection limit for GATA3 is approximately 0.2ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived human GATA3 recombinant protein (Position: M1-E197). Human GATA3 shares 95% amino acid (aa) sequence identity with mouse GATA3.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Trans-acting T-cell-specific transcription factor GATA-3, also named HDR or GATA3, is a protein that in humans is encoded by the GATA3 gene. It is mapped to 10p14. This gene belongs to the GATA family of transcription factors. It regulates luminal epithelial cell differentiation in the mammary gland. The protein contains two GATA-type zinc fingers, it is an important regulator of T cell development and plays an important role in endothelial cell biology. GATA3 has been shown to promote the secretion of IL-4, IL-5, and IL-13 from Th2 cells, and induces the differentiation of Th0 cells towards this T cell subtype while suppressing their differentiation towards Th1 cells.

Reference :

1. Joulin V, Bories D, Eleouet JF, Labastie MC, Chretien S, Mattei MG, Romeo PH (Jul 1991). "A T-cell specific TCR delta DNA binding protein is a member of the human GATA family" 2. Kouros-Mehr Hosein, Slorach EM, Sternlicht MD, Werb Z (December 2006). "GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland". Cell 127 (5): 1041–55. 3. Wilson BJ (2008). "Does GATA3 act in tissue-specific pathways? A meta-analysis-based approach". J. Carcinogenesis 7: 6.

Gene Name :

GATA3

Protein Name :

Trans-acting T-cell-specific transcription factor GATA-3

Gene Full Name :

GATA binding protein 3

Synonyms :

GATA 3 antibody GATA binding factor 3 antibody GATA binding protein 3 antibody GATA-binding factor 3 antibody Gata3 antibody GATA3_HUMAN antibody HDR antibody HDRS antibody MGC2346 antibody MGC5199 antibody MGC5445 antibody Trans acting T cell specific transcription factor GATA 3 antibody Trans-acting T-cell-specific transcription factor GATA-3 antibody

Uniprot ID :

P23771

more info or order :

Boster Immunoleader product webpage