Anti-FGFR4 Antibody | Boster Immunoleader PB9193 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-FGFR4 Antibody

catalog :

PB9193

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot, immunohistochemistry - paraffin section

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-FGFR4 Antibody

Catalog Number :

PB9193

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Fibroblast growth factor receptor 4(FGFR4) detection. Tested with WB, IHC-P in Human.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

WB,IHC-P

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Immunohistochemistry(Paraffin-embedded S ... :

Concentration: 0.5-1μg/ml; Tested Species: Human

Notes :

WB: The detection limit for FGFR4 is approximately 0.25ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived human FGFR4 recombinant protein (Position: L22-H206). Human FGFR4 shares 86% and 84% amino acid (aa) sequences identity with mouse and rat FGFR4, respectively.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

Background :

FGFR4(Fibroblast growth factor receptor 4), also known as CD334, is a protein that in humans is encoded by the FGFR4 gene. It is mapped to 5q35.2. The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. It is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis.

Reference :

1. Lesca, E., Lammens, A., Huber, R., Augustin, M. "Structural analysis of the human Fibroblast Growth Factor Receptor 4 kinase". J. Mol. Biol. 2. "Entrez Gene: FGFR4 fibroblast growth factor receptor 4

Gene Name :

FGFR4

Protein Name :

Fibroblast growth factor receptor 4

Gene Full Name :

fibroblast growth factor receptor 4

Synonyms :

CD 334 antibody CD334 antibody CD334 antigen antibody fc13h 10 antibody fc13h10 antibody Fgfr 4 antibody FGFR-4 antibody Fgfr4 antibody FGFR4_HUMAN antibody Fibroblast growth factor receptor 4 antibody Hydroxyaryl protein kinase antibody JTK 2 antibody JTK2 antibody MGC20292 antibody Protein tyrosine kinase antibody TKF antibody Tyrosine kinase related to fibroblast growth factor receptor antibody Tyrosylprotein kinase antibody

Uniprot ID :

P22455

more info or order :

Boster Immunoleader product webpage