Anti-EDA Antibody | Boster Immunoleader PB9191 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-EDA Antibody

catalog :

PB9191

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-EDA Antibody

Catalog Number :

PB9191

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Ectodysplasin-A(EDA) detection. Tested with WB in Human.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Notes :

WB: The detection limit for EDA is approximately 0.25ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived human EDA recombinant protein (Position: A30-S391). Human EDA shares 95% amino acid (aa) sequence identity with mouse EDA.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Ectodysplasin-A is a protein that in humans is encoded by the EDA gene. It is mapped to Xq13.1. The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia.

Reference :

1. Bayes, M., Hartung, A. J., Ezer, S., Pispa, J., Thesleff, I., Srivastava, A. K., Kere, J. The anhidrotic ectodermal dysplasia gene (EDA) undergoes alternative splicing and encodes ectodysplasin-A with deletion mutations in collagenous repeats. Hum. Molec. Genet. 7: 1661-1669, 1998. 2. Kere J, Srivastava AK, Montonen O, Zonana J, Thomas N, Ferguson B, Munoz F, Morgan D, Clarke A, Baybayan P, Chen EY, Ezer S, Saarialho-Kere U, de la Chapelle A, Schlessinger D (Sep 1996). "X-linked anhidrotic (hypohidrotic) ectodermal dysplasia is caused by mutation in a novel transmembrane protein". Nat Genet 13 (4): 409–16.

Gene Name :

EDA

Protein Name :

Ectodysplasin-A

Gene Full Name :

ectodysplasin A

Synonyms :

ECTD1 antibody Ectodermal dysplasia 1, anhidrotic antibody Ectodermal dysplasia protein antibody Ectodermal dysplasia, anhidrotic (hypohydrotic) antibody Ectodysplasin A antibody Ectodysplasin A, membrane form antibody Ectodysplasin A, secreted form antibody ECTODYSPLASIN A1 ISOFORM antibody ECTODYSPLASIN A2 ISOFORM antibody ECTODYSPLASIN antibody Ectodysplasin-A antibody ED1 A1 antibody ED1 A2 antibody ED1 antibody ED1 GENE antibody Eda A1 antibody Eda A2 antibody eda antibody EDA protein antibody EDA protein homolog antibody EDA_HUMAN antibody EDA1 antibody EDA1 GENE antibody EDA2 antibody HED antibody HED1 antibody ODT1 antibody Oligodontia 1 antibody secreted form antibody STHAGX1 antibody Ta antibody Tabby antibody Tabby protein antibody X linked anhidroitic ectodermal dysplasia protein antibody XHED antibody XLHED antibody

Uniprot ID :

Q92838

more info or order :

Boster Immunoleader product webpage